Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   STR_RS08750 Genome accession   NC_006449
Coordinates   1658191..1659291 (-) Length   366 a.a.
NCBI ID   WP_148148889.1    Uniprot ID   -
Organism   Streptococcus thermophilus CNRZ1066     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1653191..1664291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STR_RS08710 (str1856) - 1653803..1654000 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  STR_RS08715 (str1857) - 1654249..1655442 (-) 1194 WP_022096898.1 acetate kinase -
  STR_RS08720 (str1858) comYH 1655498..1656454 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  STR_RS08725 (str1859) comGG 1656499..1656816 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  STR_RS08730 (str1860) comYF 1656794..1657231 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  STR_RS08735 (str1861) comGE 1657215..1657508 (-) 294 WP_011227584.1 competence type IV pilus minor pilin ComGE -
  STR_RS08740 (str1862) comYD 1657480..1657908 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  STR_RS08745 (str1863) comYC 1657868..1658194 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STR_RS08750 (str1864) comYB 1658191..1659291 (-) 1101 WP_148148889.1 competence type IV pilus assembly protein ComGB Machinery gene
  STR_RS08755 (str1865) comGA/cglA/cilD 1659173..1660114 (-) 942 WP_011226629.1 competence type IV pilus ATPase ComGA Machinery gene
  STR_RS08760 (str1866) - 1660195..1660557 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41694.79 Da        Isoelectric Point: 10.0449

>NTDB_id=23993 STR_RS08750 WP_148148889.1 1658191..1659291(-) (comYB) [Streptococcus thermophilus CNRZ1066]
MPEKISKTIRLPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPSFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=23993 STR_RS08750 WP_148148889.1 1658191..1659291(-) (comYB) [Streptococcus thermophilus CNRZ1066]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTCTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.386

93.443

0.508
  comYB Streptococcus mutans UA159

54.386

93.443

0.508
  comYB Streptococcus gordonii str. Challis substr. CH1

50.877

93.443

0.475
  comGB/cglB Streptococcus mitis NCTC 12261

50.151

90.437

0.454
  comGB/cglB Streptococcus mitis SK321

49.394

90.164

0.445
  comGB/cglB Streptococcus pneumoniae Rx1

49.091

90.164

0.443
  comGB/cglB Streptococcus pneumoniae D39

49.091

90.164

0.443
  comGB/cglB Streptococcus pneumoniae R6

49.091

90.164

0.443
  comGB/cglB Streptococcus pneumoniae TIGR4

49.091

90.164

0.443
  comGB Lactococcus lactis subsp. cremoris KW2

45.758

90.164

0.413

Multiple sequence alignment