Detailed information NTG0023990

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: STR_RS08730
• Genome accession: NC_006449
• Coordinates: 1656794..1657231 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus CNRZ1066
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1651794..1662231

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR_RS08695 (str1853)	-	1651848..1652510 (-)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-
STR_RS08700 (str1854)	-	1652613..1653061 (-)	449	Protein_1646	CAAX protease	-
STR_RS11470 (str1855)	-	1653135..1653560 (-)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
STR_RS08710 (str1856)	-	1653803..1654000 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
STR_RS08715 (str1857)	-	1654249..1655442 (-)	1194	WP_022096898.1	acetate kinase	-
STR_RS08720 (str1858)	comYH	1655498..1656454 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STR_RS08725 (str1859)	comGG	1656499..1656816 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STR_RS08730 (str1860)	comYF	1656794..1657231 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
STR_RS08735 (str1861)	comGE	1657215..1657508 (-)	294	WP_011227584.1	competence type IV pilus minor pilin ComGE	-
STR_RS08740 (str1862)	comYD	1657480..1657908 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STR_RS08745 (str1863)	comYC	1657868..1658194 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STR_RS08750 (str1864)	comYB	1658191..1659291 (-)	1101	WP_148148889.1	competence type IV pilus assembly protein ComGB	Machinery gene
STR_RS08755 (str1865)	comGA/cglA/cilD	1659173..1660114 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
STR_RS08760 (str1866)	-	1660195..1660557 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=23990 STR_RS08730 WP_014608742.1 1656794..1657231(-) (comYF) [Streptococcus thermophilus CNRZ1066]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=23990 STR_RS08730 WP_014608742.1 1656794..1657231(-) (comYF) [Streptococcus thermophilus CNRZ1066]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441