Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   QMA0248_RS04460 Genome accession   NZ_CP022392
Coordinates   910873..911547 (+) Length   224 a.a.
NCBI ID   WP_003099507.1    Uniprot ID   -
Organism   Streptococcus iniae strain QMA0248     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 905873..916547
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMA0248_RS04445 (QMA0248_0899) pstB 906687..907445 (+) 759 WP_003099501.1 phosphate ABC transporter ATP-binding protein PstB -
  QMA0248_RS04450 (QMA0248_0900) phoU 907500..908153 (+) 654 WP_003099503.1 phosphate signaling complex protein PhoU -
  QMA0248_RS04455 (QMA0248_0901) - 908215..910752 (+) 2538 WP_003099506.1 M1 family metallopeptidase -
  QMA0248_RS04460 (QMA0248_0902) ciaR 910873..911547 (+) 675 WP_003099507.1 response regulator transcription factor Regulator
  QMA0248_RS04465 (QMA0248_0903) ciaH 911540..912850 (+) 1311 WP_003099509.1 sensor histidine kinase Regulator
  QMA0248_RS04470 (QMA0248_0904) rpsT 913022..913264 (-) 243 WP_080613191.1 30S ribosomal protein S20 -
  QMA0248_RS04475 (QMA0248_0905) coaA 913324..914244 (-) 921 WP_089180078.1 type I pantothenate kinase -
  QMA0248_RS04480 (QMA0248_0906) - 914404..915579 (+) 1176 WP_003099060.1 IS256 family transposase -
  QMA0248_RS04485 (QMA0248_0907) - 915827..916426 (+) 600 WP_003099513.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25562.41 Da        Isoelectric Point: 4.3757

>NTDB_id=238988 QMA0248_RS04460 WP_003099507.1 910873..911547(+) (ciaR) [Streptococcus iniae strain QMA0248]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGFYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KESLDDKGHGFDLGADDYLTKPFYLEELKMRIQALLKRTGKMTTSQLSYGNISIDTERNMVKVGDTTIELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVDNLQTLRSVGYILKTNG

Nucleotide


Download         Length: 675 bp        

>NTDB_id=238988 QMA0248_RS04460 WP_003099507.1 910873..911547(+) (ciaR) [Streptococcus iniae strain QMA0248]
ATGATAAAAATATTACTTGTTGAAGATGATTTAAGTTTATCTAATTCGATTTTTGATTTTTTAGATGATTTTGCTGATGT
TATGCAGGTTTTTGATGGAGATGAAGGTTTTTATGAGGCTGAAAGTGGTGTTTATGATCTTATTCTCCTGGACTTAATGT
TACCTGAAAAAAATGGTTTTCAAGTCCTAAAAGAATTAAGAGAAAAAGACATCAAAACGCCTGTTCTTATTATGACTGCT
AAAGAAAGTCTTGACGATAAAGGGCATGGCTTTGACCTTGGAGCTGATGACTACCTAACCAAACCATTTTATTTAGAGGA
GCTAAAAATGCGTATTCAAGCCCTCTTGAAACGAACTGGTAAGATGACTACCAGTCAGCTATCTTATGGGAATATCAGTA
TTGATACTGAACGAAATATGGTAAAAGTCGGAGACACTACCATTGAGCTTCTTGGAAAAGAGTATGATTTACTCATTTAT
CTCCTTCAAAATCAAAATGTTATTTTACCTAAATCACAGATTTTTGACCGTATATGGGGATTCGACAGTGATACCACAAT
ATCAGTTGTAGAGGTTTATGTTTCAAAAATCAGAAAAAAACTAAAAGGGACAGATTTTGTAGACAACCTTCAAACGCTTA
GAAGTGTCGGATACATCTTAAAAACAAATGGCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.767

100

0.393
  covR Streptococcus salivarius strain HSISS4

36.726

100

0.371

Multiple sequence alignment