Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   QMA0248_RS04465 Genome accession   NZ_CP022392
Coordinates   911540..912850 (+) Length   436 a.a.
NCBI ID   WP_003099509.1    Uniprot ID   A0A3L8GJR1
Organism   Streptococcus iniae strain QMA0248     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 906540..917850
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMA0248_RS04445 (QMA0248_0899) pstB 906687..907445 (+) 759 WP_003099501.1 phosphate ABC transporter ATP-binding protein PstB -
  QMA0248_RS04450 (QMA0248_0900) phoU 907500..908153 (+) 654 WP_003099503.1 phosphate signaling complex protein PhoU -
  QMA0248_RS04455 (QMA0248_0901) - 908215..910752 (+) 2538 WP_003099506.1 M1 family metallopeptidase -
  QMA0248_RS04460 (QMA0248_0902) ciaR 910873..911547 (+) 675 WP_003099507.1 response regulator transcription factor Regulator
  QMA0248_RS04465 (QMA0248_0903) ciaH 911540..912850 (+) 1311 WP_003099509.1 sensor histidine kinase Regulator
  QMA0248_RS04470 (QMA0248_0904) rpsT 913022..913264 (-) 243 WP_080613191.1 30S ribosomal protein S20 -
  QMA0248_RS04475 (QMA0248_0905) coaA 913324..914244 (-) 921 WP_089180078.1 type I pantothenate kinase -
  QMA0248_RS04480 (QMA0248_0906) - 914404..915579 (+) 1176 WP_003099060.1 IS256 family transposase -
  QMA0248_RS04485 (QMA0248_0907) - 915827..916426 (+) 600 WP_003099513.1 class I SAM-dependent methyltransferase -
  QMA0248_RS04490 (QMA0248_0908) - 916413..917690 (+) 1278 WP_089180079.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49969.52 Da        Isoelectric Point: 9.1099

>NTDB_id=238989 QMA0248_RS04465 WP_003099509.1 911540..912850(+) (ciaH) [Streptococcus iniae strain QMA0248]
MANLKRIYQSDNFGHFFHFFAVFTGIFVVMTMIIIQIMQYGVYSSVDSSLLAVSKNSSVYANLTMERMTSFYFDNQEDAF
KNGTEVFKAALVEQPVANTDIILFSSNGTVLNSFDALSGFQNFTLKTNELNAIRTRKLMNFYGHEEKYHTLTVKIHSNRY
PAVAYLMAVVNVEQLDRANERYERIIVLVMITFWFISVLASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LETLFRKPNETILENSEPIASSLEEVRNMKILTTNLLNLARRDDGINPELVDVDASFFDAMFENFNLVAEDYGKDFHFEN
QVKRTIKMDKSLLKQLITILFDNALKYTDSDGQISISVRTTDKNLMVRVLDDGPGIKDMDKKKVFDRFYRVDKARTRTKG
GFGLGLSLAKQIVASLNGTISVKDNKPKGTIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=238989 QMA0248_RS04465 WP_003099509.1 911540..912850(+) (ciaH) [Streptococcus iniae strain QMA0248]
ATGGCTAATTTAAAACGTATTTACCAGTCAGATAATTTTGGGCATTTTTTCCATTTTTTTGCAGTCTTTACAGGAATATT
TGTTGTCATGACCATGATTATCATTCAAATCATGCAGTACGGTGTTTATTCTTCGGTAGATAGTAGTCTACTTGCTGTGT
CAAAAAATTCATCGGTTTATGCTAATTTAACCATGGAACGAATGACCTCATTTTACTTTGATAATCAAGAGGATGCTTTT
AAAAATGGAACTGAAGTCTTTAAAGCAGCCTTAGTTGAACAACCAGTTGCCAATACGGATATTATCCTCTTTAGTTCTAA
CGGAACGGTTTTAAATAGCTTTGATGCGCTATCGGGTTTTCAAAATTTTACCTTAAAAACAAATGAATTAAATGCCATTC
GAACACGGAAATTGATGAATTTTTACGGGCATGAAGAAAAATACCATACGCTGACAGTTAAGATTCATTCCAATAGGTAC
CCAGCGGTGGCTTACCTAATGGCAGTTGTCAATGTGGAACAATTGGACCGTGCCAATGAGCGCTATGAACGAATCATTGT
TCTTGTTATGATAACTTTCTGGTTTATTTCTGTTTTGGCCAGTATATACCTTGCAAAATGGAGTCGTAAACCAATTCTTG
AAAGTTATGAGAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAATTAAGAACTCCCTTAGCAGTATTACAAAATCGC
TTAGAGACCCTGTTTAGAAAACCTAATGAAACAATTCTGGAAAACAGTGAACCAATTGCTTCGAGTTTAGAAGAAGTGCG
CAATATGAAGATCTTAACCACAAATTTATTGAATCTTGCCAGACGCGATGATGGGATTAATCCAGAACTCGTTGATGTGG
ATGCAAGCTTTTTTGACGCTATGTTTGAAAACTTCAACTTAGTAGCTGAAGATTATGGTAAAGACTTCCATTTTGAAAAT
CAGGTTAAGCGGACAATAAAAATGGATAAATCTTTATTAAAACAATTGATTACCATTTTATTTGATAATGCTTTGAAATA
CACGGACTCTGATGGGCAAATTTCAATTAGTGTTCGAACAACAGATAAAAATTTAATGGTCAGAGTGCTAGATGATGGTC
CTGGAATAAAAGACATGGATAAAAAGAAAGTTTTTGACCGCTTCTATCGTGTTGATAAGGCTAGAACACGTACTAAAGGT
GGATTTGGTTTGGGACTTTCTTTAGCAAAACAGATTGTTGCTTCCTTAAATGGAACAATATCAGTTAAAGACAATAAACC
AAAAGGGACAATATTTGAAGTTAAACTCTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L8GJR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.275

99.312

0.569
  ciaH Streptococcus pneumoniae Rx1

51.835

100

0.518
  ciaH Streptococcus pneumoniae D39

51.835

100

0.518
  ciaH Streptococcus pneumoniae R6

51.835

100

0.518
  ciaH Streptococcus pneumoniae TIGR4

51.835

100

0.518

Multiple sequence alignment