Detailed information NTG0023452

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: M6_RS04460
• Genome accession: NC_006086
• Coordinates: 882762..883598 (+)
• Length: 278 a.a.
• NCBI ID: WP_011184519.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS10394
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 877762..888598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M6_RS04430 (M6_Spy0874)	-	878250..878684 (+)	435	WP_011017767.1	hypothetical protein	-
M6_RS04435 (M6_Spy0875)	-	878734..879645 (-)	912	WP_011184516.1	diacylglycerol/lipid kinase family protein	-
M6_RS04440 (M6_Spy0876)	trhA	879762..880412 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
M6_RS04445 (M6_Spy0877)	-	880409..880849 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
M6_RS04450 (M6_Spy0878)	ylqF	881068..881916 (+)	849	WP_011184517.1	ribosome biogenesis GTPase YlqF	-
M6_RS04455 (M6_Spy0879)	-	881906..882697 (+)	792	WP_011184518.1	ribonuclease HII	-
M6_RS04460 (M6_Spy0880)	dprA	882762..883598 (+)	837	WP_011184519.1	DNA-processing protein DprA	Machinery gene
M6_RS04465 (M6_Spy0881)	topA	883705..885834 (+)	2130	WP_011184520.1	type I DNA topoisomerase	-
M6_RS04470 (M6_Spy0882)	trmFO	885969..887315 (+)	1347	WP_021340038.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31136.17 Da
• Isoelectric Point: 9.2335

>NTDB_id=23452 M6_RS04460 WP_011184519.1 882762..883598(+) (dprA) [Streptococcus pyogenes MGAS10394]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMYILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=23452 M6_RS04460 WP_011184519.1 882762..883598(+) (dprA) [Streptococcus pyogenes MGAS10394]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCTATTGTTGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGTATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363