Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   BB159_RS11090 Genome accession   NZ_CP021868
Coordinates   2145484..2146713 (+) Length   409 a.a.
NCBI ID   WP_000728357.1    Uniprot ID   A0AAD2WWM9
Organism   Streptococcus agalactiae strain SG-M8     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2140484..2151713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BB159_RS11065 (BB159_11065) - 2141646..2144225 (+) 2580 WP_000154429.1 YfhO family protein -
  BB159_RS11085 (BB159_11085) rlmH 2144804..2145283 (-) 480 WP_000768333.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  BB159_RS11090 (BB159_11090) htrA 2145484..2146713 (+) 1230 WP_000728357.1 S1C family serine protease Regulator
  BB159_RS11095 (BB159_11095) spo0J 2146811..2147584 (+) 774 WP_000456084.1 ParB/RepB/Spo0J family partition protein Regulator
  BB159_RS11100 (BB159_11100) dnaA 2147793..2149154 (+) 1362 WP_000138202.1 chromosomal replication initiator protein DnaA -
  BB159_RS11105 (BB159_11105) dnaN 2149309..2150445 (+) 1137 WP_000581132.1 DNA polymerase III subunit beta -
  BB159_RS11110 (BB159_11110) - 2150503..2151395 (+) 893 Protein_2091 diacylglycerol/lipid kinase family protein -
  BB159_RS11115 (BB159_11115) - 2151405..2151602 (+) 198 WP_000285199.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 43090.54 Da        Isoelectric Point: 9.5271

>NTDB_id=234199 BB159_RS11090 WP_000728357.1 2145484..2146713(+) (htrA) [Streptococcus agalactiae strain SG-M8]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=234199 BB159_RS11090 WP_000728357.1 2145484..2146713(+) (htrA) [Streptococcus agalactiae strain SG-M8]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCCGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAAGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(106-251)

PDZ domain (PDZ_2)

(300-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

63.359

96.088

0.609
  htrA Streptococcus gordonii str. Challis substr. CH1

57.357

98.044

0.562
  htrA Streptococcus mitis NCTC 12261

56.533

97.311

0.55
  htrA Streptococcus pneumoniae TIGR4

55.037

99.511

0.548
  htrA Streptococcus pneumoniae Rx1

55.037

99.511

0.548
  htrA Streptococcus pneumoniae D39

55.037

99.511

0.548
  htrA Streptococcus pneumoniae R6

55.037

99.511

0.548

Multiple sequence alignment