Detailed information NTG0233303

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: CDH81_RS07090
• Genome accession: NZ_CP021772
• Coordinates: 1396157..1397386 (+)
• Length: 409 a.a.
• NCBI ID: WP_000728357.1
• Uniprot ID: A0AAD2WWM9
• Organism: Streptococcus agalactiae strain B111
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1391157..1402386

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CDH81_RS07065 (CDH81_06985)	-	1392319..1394898 (+)	2580	WP_000154429.1	YfhO family protein	-
CDH81_RS07085 (CDH81_07005)	rlmH	1395477..1395956 (-)	480	WP_000768333.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
CDH81_RS07090 (CDH81_07010)	htrA	1396157..1397386 (+)	1230	WP_000728357.1	trypsin-like peptidase domain-containing protein	Regulator
CDH81_RS07095 (CDH81_07015)	spo0J	1397484..1398257 (+)	774	WP_000456084.1	ParB/RepB/Spo0J family partition protein	Regulator
CDH81_RS07100 (CDH81_07020)	dnaA	1398466..1399827 (+)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
CDH81_RS07105 (CDH81_07025)	dnaN	1399982..1401118 (+)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
CDH81_RS07110 (CDH81_07030)	-	1401176..1402068 (+)	893	Protein_1375	diacylglycerol kinase family protein	-
CDH81_RS07115 (CDH81_07035)	-	1402078..1402275 (+)	198	WP_000285199.1	DUF951 family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43090.54 Da
• Isoelectric Point: 9.5271

>NTDB_id=233303 CDH81_RS07090 WP_000728357.1 1396157..1397386(+) (htrA) [Streptococcus agalactiae strain B111]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=233303 CDH81_RS07090 WP_000728357.1 1396157..1397386(+) (htrA) [Streptococcus agalactiae strain B111]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCCGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAAGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.359	96.088	0.609
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.533	97.311	0.55
htrA	Streptococcus pneumoniae TIGR4	55.037	99.511	0.548
htrA	Streptococcus pneumoniae Rx1	55.037	99.511	0.548
htrA	Streptococcus pneumoniae D39	55.037	99.511	0.548
htrA	Streptococcus pneumoniae R6	55.037	99.511	0.548