Detailed information NTG0233213

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: CDH83_RS10030
• Genome accession: NZ_CP021770
• Coordinates: 1965420..1966649 (+)
• Length: 409 a.a.
• NCBI ID: WP_000728358.1
• Uniprot ID: A0AAW3HT93
• Organism: Streptococcus agalactiae strain B508
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1960420..1971649

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CDH83_RS10005 (CDH83_09935)	-	1961582..1964161 (+)	2580	WP_000154437.1	YfhO family protein	-
CDH83_RS10025 (CDH83_09955)	rlmH	1964740..1965219 (-)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
CDH83_RS10030 (CDH83_09960)	htrA	1965420..1966649 (+)	1230	WP_000728358.1	trypsin-like peptidase domain-containing protein	Regulator
CDH83_RS10035 (CDH83_09965)	spo0J	1966747..1967520 (+)	774	WP_000456087.1	ParB/RepB/Spo0J family partition protein	Regulator
CDH83_RS10040 (CDH83_09970)	dnaA	1967719..1969079 (+)	1361	Protein_1894	chromosomal replication initiator protein DnaA	-
CDH83_RS10045 (CDH83_09975)	dnaN	1969234..1970370 (+)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
CDH83_RS10050 (CDH83_09980)	-	1970428..1971321 (+)	894	WP_000987446.1	diacylglycerol kinase family protein	-
CDH83_RS10055 (CDH83_09985)	-	1971331..1971528 (+)	198	WP_000285199.1	DUF951 family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43118.59 Da
• Isoelectric Point: 9.5271

>NTDB_id=233213 CDH83_RS10030 WP_000728358.1 1965420..1966649(+) (htrA) [Streptococcus agalactiae strain B508]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVVSPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=233213 CDH83_RS10030 WP_000728358.1 1965420..1966649(+) (htrA) [Streptococcus agalactiae strain B508]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGTATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGGGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.104	96.088	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.281	97.311	0.548
htrA	Streptococcus pneumoniae TIGR4	54.791	99.511	0.545
htrA	Streptococcus pneumoniae Rx1	54.791	99.511	0.545
htrA	Streptococcus pneumoniae D39	54.791	99.511	0.545
htrA	Streptococcus pneumoniae R6	54.791	99.511	0.545