Detailed information NTG0233200

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: CDH83_RS04080
• Genome accession: NZ_CP021770
• Coordinates: 797254..798096 (-)
• Length: 280 a.a.
• NCBI ID: WP_001015240.1
• Uniprot ID: Q8DZU1
• Organism: Streptococcus agalactiae strain B508
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 792254..803096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CDH83_RS04070 (CDH83_04020)	-	794201..794902 (-)	702	WP_000120355.1	ABC transporter ATP-binding protein	-
CDH83_RS04075 (CDH83_04025)	topA	795039..797159 (-)	2121	WP_000246611.1	type I DNA topoisomerase	-
CDH83_RS04080 (CDH83_04030)	dprA	797254..798096 (-)	843	WP_001015240.1	DNA-processing protein DprA	Machinery gene
CDH83_RS04085 (CDH83_04035)	-	798234..799262 (-)	1029	WP_000162771.1	siderophore ABC transporter substrate-binding protein	-
CDH83_RS04090 (CDH83_04040)	-	799324..800085 (-)	762	WP_000614752.1	ATP-binding cassette domain-containing protein	-
CDH83_RS04095 (CDH83_04045)	-	800082..801056 (-)	975	WP_000588576.1	iron chelate uptake ABC transporter family permease subunit	-
CDH83_RS04100 (CDH83_04050)	-	801053..802015 (-)	963	WP_000735588.1	iron chelate uptake ABC transporter family permease subunit	-
CDH83_RS04105 (CDH83_04055)	-	802254..802802 (-)	549	WP_000136509.1	sugar O-acetyltransferase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31294.36 Da
• Isoelectric Point: 9.3802

>NTDB_id=233200 CDH83_RS04080 WP_001015240.1 797254..798096(-) (dprA) [Streptococcus agalactiae strain B508]
MNHFELFKLKKAGLTNLNIHNIINYLKKNSLTSLSVRNMAVVSKCKNPTFFIENYKQLDLKKLRQEFKKFPVLSILDSNY
PLELKEIYNPPVLLFYQGNIELLSKPKLAVVGARQASQIGCQSVKKIIKETNNQFVIVSGLARGIDTAAHVSALKNGGSS
IAVIGSGLDVYYPTENKKLQEYMSYNHLVLSEYFTGEQPLKFHFPERNRIIAGLCQGIVVAEAKMRSGSLITCERALEEG
REVFAIPGNIIDGKSDGCHHLIQEGAKCIISGKDILSEYQ

Nucleotide

• Length: 843 bp

>NTDB_id=233200 CDH83_RS04080 WP_001015240.1 797254..798096(-) (dprA) [Streptococcus agalactiae strain B508]
ATGAATCATTTTGAACTATTTAAGCTTAAAAAAGCTGGATTAACAAATCTTAATATCCACAATATTATCAACTATCTCAA
AAAGAATAGTTTAACTTCTCTATCTGTTCGCAATATGGCCGTAGTATCAAAATGTAAAAATCCTACTTTCTTTATAGAAA
ATTATAAACAGCTAGACCTTAAAAAACTTCGACAAGAATTCAAAAAATTTCCAGTTCTATCGATTTTGGATTCTAACTAT
CCTTTAGAGTTAAAAGAAATATATAATCCACCAGTTCTACTTTTTTATCAGGGTAATATTGAACTTCTATCTAAACCTAA
ATTAGCTGTAGTGGGGGCAAGACAGGCATCTCAGATAGGTTGTCAGTCTGTTAAAAAGATTATCAAGGAGACTAACAATC
AATTTGTTATCGTAAGTGGTTTAGCGCGTGGCATTGATACAGCAGCACATGTTAGTGCTTTAAAAAATGGCGGCAGTAGT
ATAGCTGTTATCGGGAGTGGTTTAGATGTTTATTATCCAACGGAGAATAAGAAACTTCAAGAATATATGTCATATAATCA
TCTCGTATTATCAGAATATTTTACCGGAGAACAACCCTTGAAATTTCATTTCCCCGAACGTAACCGTATTATTGCAGGGC
TGTGTCAAGGTATTGTGGTTGCCGAAGCTAAGATGAGATCTGGAAGTTTAATTACCTGTGAAAGAGCATTAGAAGAGGGA
CGAGAAGTTTTTGCCATTCCCGGAAATATTATCGATGGCAAATCAGATGGATGCCACCATCTTATCCAAGAAGGAGCTAA
ATGCATTATTTCAGGAAAAGATATCCTTTCTGAATATCAGTAG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-63)

3D structure

• AlphaFold DB: Q8DZU1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70.251	99.643	0.7
dprA/cilB/dalA	Streptococcus mitis SK321	62.5	100	0.625
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae D39	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae R6	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	61.786	100	0.618
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	61.429	100	0.614
dprA	Lactococcus lactis subsp. cremoris KW2	60.932	99.643	0.607
dprA	Latilactobacillus sakei subsp. sakei 23K	42.231	89.643	0.379