Detailed information NTG0224565

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: C2E56_RS01120
• Genome accession: NZ_CP026084
• Coordinates: 190858..191319 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874060.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain NJ1606
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 185858..196319

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2E56_RS01090 (C2E56_01110)	-	187474..187839 (+)	366	WP_000285373.1	DUF1033 family protein	-
C2E56_RS01095 (C2E56_01120)	comGA	188011..188982 (+)	972	WP_000250799.1	competence type IV pilus ATPase ComGA	Machinery gene
C2E56_RS01100 (C2E56_01125)	comGB	188876..189919 (+)	1044	WP_228322108.1	competence type IV pilus assembly protein ComGB	Machinery gene
C2E56_RS01105 (C2E56_01130)	comGC/cglC	189916..190245 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
C2E56_RS01110 (C2E56_01135)	comGD	190220..190633 (+)	414	WP_017646959.1	competence type IV pilus minor pilin ComGD	Machinery gene
C2E56_RS01115 (C2E56_01140)	comGE	190605..190904 (+)	300	WP_025195478.1	competence type IV pilus minor pilin ComGE	Machinery gene
C2E56_RS01120 (C2E56_01145)	comGF	190858..191319 (+)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	Machinery gene
C2E56_RS01125 (C2E56_01150)	comGG	191297..191668 (+)	372	WP_000601103.1	competence type IV pilus minor pilin ComGG	Machinery gene
C2E56_RS01130 (C2E56_01155)	comGH	191783..192757 (+)	975	WP_001008568.1	class I SAM-dependent methyltransferase	Machinery gene
C2E56_RS01135 (C2E56_01160)	-	192789..193982 (+)	1194	WP_000047537.1	acetate kinase	-
C2E56_RS01140 (C2E56_01165)	-	194134..194340 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
C2E56_RS10810 (C2E56_01170)	-	194399..194536 (+)	138	WP_079263416.1	hypothetical protein	-
C2E56_RS01145 (C2E56_01175)	-	194639..195031 (+)	393	WP_001265365.1	hypothetical protein	-
C2E56_RS01150 (C2E56_01180)	-	195100..195765 (+)	666	WP_000008107.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17861.86 Da
• Isoelectric Point: 9.8392

>NTDB_id=224565 C2E56_RS01120 WP_001874060.1 190858..191319(+) (comGF) [Streptococcus agalactiae strain NJ1606]
MKVIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=224565 C2E56_RS01120 WP_001874060.1 190858..191319(+) (comGF) [Streptococcus agalactiae strain NJ1606]
TTGAAGGTAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATTACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAAACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373