Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   C2E56_RS01130 Genome accession   NZ_CP026084
Coordinates   191783..192757 (+) Length   324 a.a.
NCBI ID   WP_001008568.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NJ1606     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 186783..197757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E56_RS01090 (C2E56_01110) - 187474..187839 (+) 366 WP_000285373.1 DUF1033 family protein -
  C2E56_RS01095 (C2E56_01120) comGA 188011..188982 (+) 972 WP_000250799.1 competence type IV pilus ATPase ComGA Machinery gene
  C2E56_RS01100 (C2E56_01125) comGB 188876..189919 (+) 1044 WP_228322108.1 competence type IV pilus assembly protein ComGB Machinery gene
  C2E56_RS01105 (C2E56_01130) comGC/cglC 189916..190245 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  C2E56_RS01110 (C2E56_01135) comGD 190220..190633 (+) 414 WP_017646959.1 competence type IV pilus minor pilin ComGD Machinery gene
  C2E56_RS01115 (C2E56_01140) comGE 190605..190904 (+) 300 WP_025195478.1 competence type IV pilus minor pilin ComGE Machinery gene
  C2E56_RS01120 (C2E56_01145) comGF 190858..191319 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF Machinery gene
  C2E56_RS01125 (C2E56_01150) comGG 191297..191668 (+) 372 WP_000601103.1 competence type IV pilus minor pilin ComGG Machinery gene
  C2E56_RS01130 (C2E56_01155) comGH 191783..192757 (+) 975 WP_001008568.1 class I SAM-dependent methyltransferase Machinery gene
  C2E56_RS01135 (C2E56_01160) - 192789..193982 (+) 1194 WP_000047537.1 acetate kinase -
  C2E56_RS01140 (C2E56_01165) - 194134..194340 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  C2E56_RS10810 (C2E56_01170) - 194399..194536 (+) 138 WP_079263416.1 hypothetical protein -
  C2E56_RS01145 (C2E56_01175) - 194639..195031 (+) 393 WP_001265365.1 hypothetical protein -
  C2E56_RS01150 (C2E56_01180) - 195100..195765 (+) 666 WP_000008107.1 CPBP family intramembrane glutamic endopeptidase -
  C2E56_RS01155 (C2E56_01185) proC 195786..196556 (-) 771 WP_161508486.1 pyrroline-5-carboxylate reductase -
  C2E56_RS01160 (C2E56_01190) pepA 196626..197693 (-) 1068 WP_001281326.1 glutamyl aminopeptidase -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 37200.19 Da        Isoelectric Point: 4.4491

>NTDB_id=224567 C2E56_RS01130 WP_001008568.1 191783..192757(+) (comGH) [Streptococcus agalactiae strain NJ1606]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGCS
VQFIQEDAVRPQILKESDVIISDLPVGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWRRENSHYSK
NMIE

Nucleotide


Download         Length: 975 bp        

>NTDB_id=224567 C2E56_RS01130 WP_001008568.1 191783..192757(+) (comGH) [Streptococcus agalactiae strain NJ1606]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAATCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTGTAGT
GTCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGAAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(70-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

67.302

97.222

0.654
  comGH Streptococcus mutans UA140

67.302

97.222

0.654