Detailed information NTG0223282

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: A6J87_RS09950
• Genome accession: NZ_CP020451
• Coordinates: 2065241..2066080 (+)
• Length: 279 a.a.
• NCBI ID: WP_080611997.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_259
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2060241..2071080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J87_RS09920 (A6J87_09860)	-	2060658..2061185 (+)	528	WP_080611994.1	ECF transporter S component	-
A6J87_RS09925 (A6J87_09865)	-	2061208..2061723 (+)	516	WP_080611995.1	transcription repressor NadR	-
A6J87_RS09930 (A6J87_09870)	-	2061818..2062507 (+)	690	WP_013990509.1	XRE family transcriptional regulator	-
A6J87_RS09935 (A6J87_09875)	ylqF	2062636..2063490 (+)	855	WP_014634567.1	ribosome biogenesis GTPase YlqF	-
A6J87_RS09940 (A6J87_09880)	-	2063477..2064247 (+)	771	WP_064521303.1	ribonuclease HII	-
A6J87_RS09945 (A6J87_09885)	-	2064254..2065174 (+)	921	WP_080611996.1	ROK family protein	-
A6J87_RS09950 (A6J87_09890)	dprA	2065241..2066080 (+)	840	WP_080611997.1	DNA-processing protein DprA	Machinery gene
A6J87_RS09955 (A6J87_09895)	topA	2066248..2068392 (+)	2145	WP_073949738.1	type I DNA topoisomerase	-
A6J87_RS09960 (A6J87_09900)	-	2068575..2069252 (+)	678	WP_073949740.1	ATP-binding cassette domain-containing protein	-
A6J87_RS09965 (A6J87_09905)	-	2069239..2069982 (+)	744	WP_080611998.1	lantibiotic ABC transporter permease	-
A6J87_RS09970 (A6J87_09910)	-	2069975..2070616 (+)	642	WP_155197880.1	nisG	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31293.25 Da
• Isoelectric Point: 8.6585

>NTDB_id=223282 A6J87_RS09950 WP_080611997.1 2065241..2066080(+) (dprA) [Streptococcus salivarius strain FDAARGOS_259]
MNNFELFKLKAAGLTNLNILNILDYQKTQDRKLSLRDMAVVSKSKNAVLFMEKYKSLDIKQLKEQFERFPTLSIFDKEYP
IELKHTYNPPVLLYYQGNLDLLSKPKLAVVGARKCSETGKQSVRKIVSELGNHFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDILSEFS

Nucleotide

• Length: 840 bp

>NTDB_id=223282 A6J87_RS09950 WP_080611997.1 2065241..2066080(+) (dprA) [Streptococcus salivarius strain FDAARGOS_259]
ATGAATAATTTTGAACTTTTTAAACTTAAAGCCGCTGGGTTGACGAATTTGAATATCTTAAATATTTTGGACTATCAAAA
AACTCAAGATAGAAAATTGAGTTTACGTGATATGGCAGTGGTATCCAAGTCTAAAAATGCCGTTCTTTTTATGGAAAAGT
ATAAGAGTTTAGATATTAAGCAACTTAAAGAACAGTTTGAACGTTTTCCTACGCTATCGATTTTTGATAAAGAATATCCC
ATTGAGCTGAAGCATACCTATAATCCTCCTGTTCTTCTTTATTATCAGGGAAATCTTGATTTACTGAGTAAACCAAAGCT
AGCTGTTGTTGGGGCAAGAAAGTGTTCTGAAACAGGCAAACAGTCCGTTCGCAAAATTGTTAGTGAACTTGGAAATCACT
TTACTATTGTGAGTGGATTGGCGCGTGGGATTGATACTTGTGCGCATATGGAGGCCTTGAAAAATAAGGGAAACACTATT
GCAGTTATCGGGACAGGACTTGATGTTTATTATCCTAAAGAAAATAAAGCTTTGCAGGACTATATGGCCAAAAATCATTT
AGTTCTTACTGAATATGGACCGGGTGAACAGCCTCTCAAGTACCATTTTCCTGAACGTAATCGGATTATTTCTGGATTGT
GTCAAGGAGTTATGGTCGTAGAAGCAAAACTTCGCTCTGGAAGTCTGATTACTTGTGAGCGTGCCATGGAAGAAGGTAGA
GATGTTTTTGCTATTCCAGGAAATATTTTAGATGGAAAGTCAGACGGATGTCATCACTTAATTCAAGAGGGTGCAAAGTG
CATCACGACAGGGTTTGACATCCTATCAGAGTTTTCTTGA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	72.043	100	0.72
dprA/cilB/dalA	Streptococcus mitis SK321	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.95	99.642	0.627
dprA	Lactococcus lactis subsp. cremoris KW2	59.712	99.642	0.595
dprA	Latilactobacillus sakei subsp. sakei 23K	40.927	92.832	0.38
dprA	Bacillus subtilis subsp. subtilis str. 168	48.095	75.269	0.362