Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   A6J85_RS03880 Genome accession   NZ_CP020450
Coordinates   789158..790516 (+) Length   452 a.a.
NCBI ID   WP_081102626.1    Uniprot ID   A0AB35FQC2
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 784158..795516
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS03850 (A6J85_03810) dnaA 784440..785792 (-) 1353 WP_008808037.1 chromosomal replication initiator protein DnaA -
  A6J85_RS03855 (A6J85_03815) spo0J 785996..786760 (-) 765 WP_008808036.1 ParB/RepB/Spo0J family partition protein Regulator
  A6J85_RS03860 (A6J85_03820) htrA 786826..788019 (-) 1194 WP_008808035.1 S1C family serine protease Regulator
  A6J85_RS03865 (A6J85_03825) rlmH 788213..788692 (+) 480 WP_008808034.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  A6J85_RS03875 (A6J85_03835) comC/comC1 788978..789142 (+) 165 WP_080998577.1 bacteriocin Regulator
  A6J85_RS03880 (A6J85_03840) comD/comD1 789158..790516 (+) 1359 WP_081102626.1 competence system sensor histidine kinase ComD Regulator
  A6J85_RS03885 (A6J85_03845) comE/comE2 790513..791280 (+) 768 WP_008808031.1 competence system response regulator transcription factor ComE Regulator
  A6J85_RS03900 (A6J85_03860) ychF 791602..792717 (+) 1116 WP_061586345.1 redox-regulated ATPase YchF -
  A6J85_RS03905 (A6J85_03865) pth 792791..793360 (+) 570 WP_060970646.1 aminoacyl-tRNA hydrolase -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 52667.10 Da        Isoelectric Point: 5.5229

>NTDB_id=223161 A6J85_RS03880 WP_081102626.1 789158..790516(+) (comD/comD1) [Streptococcus gordonii strain FDAARGOS_257]
MNFEKIFAIFSLLVQTISFVTVYKKICDIKKLNISIIFLYLTISFSSLILAQFYNLLPEYGDVLSTFLHYLLIFFQPLIL
HLYFSKKGLYKGYVSIFLSLLIYLSVSSSETFFSVIISSVTGDDFVNQYWGSYYTIVNILALFFVLKSFEFFEFEFSYFK
NFDFEKEIMNVIKIYVTIHILLNISHWFSENAHLNSFASMIATIGFIMFLSTLFYLKSAREQYEKAKEIQQKKEEQRQLQ
LYTDEIVGLYNEIRGFRHDYAGMLTSLQTGINSGDMKEVERIFHNVLSQANISLRSDDYTFFELNNVQDTALRSVLIQTI
FKARECGVEIVFEMKDVIETLPMKLLDLVRVASVLLNNAVEGAAESPSKTMNVSLVKLDKEIVFVIQNSRQSRYINLEEI
YEVGFSTKGENRGLGLNNVKEIIDKYDEVILETDIETNYFIQVVRFKRKEKI

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=223161 A6J85_RS03880 WP_081102626.1 789158..790516(+) (comD/comD1) [Streptococcus gordonii strain FDAARGOS_257]
ATGAATTTTGAAAAAATATTTGCTATTTTCTCTTTACTAGTTCAAACAATTTCTTTTGTTACTGTATACAAAAAAATATG
TGATATAAAAAAATTAAATATTTCTATCATATTTCTGTACTTAACAATAAGTTTTAGTAGTTTGATATTAGCACAGTTTT
ATAATTTATTACCCGAATATGGAGATGTATTAAGTACTTTCTTACATTACTTACTTATATTTTTCCAACCACTAATCTTA
CATTTATATTTTTCTAAAAAAGGATTATATAAAGGATATGTATCTATCTTTTTATCCCTACTTATATATCTTTCTGTATC
ATCTTCTGAAACTTTTTTCTCAGTTATTATATCTTCAGTGACAGGAGATGATTTTGTTAATCAATACTGGGGTTCTTACT
ATACTATAGTAAATATCTTAGCATTATTTTTTGTTTTGAAATCTTTTGAATTTTTTGAGTTTGAATTTAGTTATTTTAAA
AATTTTGATTTTGAAAAAGAAATAATGAATGTAATTAAAATTTATGTAACGATTCATATCTTATTAAATATTTCTCATTG
GTTCAGCGAAAATGCACATCTTAATAGCTTTGCTAGTATGATTGCAACTATAGGATTTATTATGTTTTTGTCGACCTTAT
TTTATCTGAAGTCTGCTCGTGAACAATATGAAAAAGCTAAAGAAATTCAGCAAAAAAAGGAAGAACAAAGACAACTACAA
CTTTATACAGATGAAATTGTAGGTCTTTATAACGAAATTCGAGGTTTTCGTCACGATTATGCTGGTATGTTAACAAGTTT
GCAAACCGGAATTAACTCAGGTGATATGAAAGAAGTAGAGCGAATCTTTCATAATGTTTTAAGTCAAGCTAATATTTCCC
TTCGATCAGATGACTATACTTTTTTTGAGTTAAATAATGTTCAAGACACTGCCTTGAGAAGTGTGTTAATTCAAACTATA
TTTAAGGCTCGAGAGTGTGGAGTAGAGATCGTATTTGAAATGAAGGATGTTATTGAGACATTACCTATGAAACTTTTAGA
TTTAGTTCGAGTAGCTAGTGTATTGCTCAATAATGCGGTTGAAGGGGCAGCTGAAAGTCCCTCAAAAACAATGAACGTGT
CTTTAGTAAAGCTAGATAAAGAAATTGTTTTTGTAATTCAGAATTCTCGTCAAAGCCGTTACATTAATTTAGAAGAAATT
TATGAAGTAGGCTTCTCGACAAAAGGAGAAAATCGAGGATTAGGTTTAAATAATGTCAAAGAAATTATTGACAAATATGA
TGAAGTTATTCTGGAAACAGATATAGAAACAAATTATTTTATACAAGTTGTAAGATTTAAAAGAAAGGAAAAAATATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(343-444)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

77.042

100

0.772
  comD/comD2 Streptococcus gordonii strain NCTC7865

77.852

98.894

0.77
  comD/comD2 Streptococcus pneumoniae TIGR4

49.34

83.85

0.414
  comD/comD1 Streptococcus pneumoniae Rx1

49.077

83.85

0.412
  comD/comD1 Streptococcus pneumoniae D39

49.077

83.85

0.412
  comD/comD1 Streptococcus pneumoniae R6

49.077

83.85

0.412
  comD Streptococcus mitis NCTC 12261

48.285

83.85

0.405
  comD Streptococcus mitis SK321

48.404

83.186

0.403

Multiple sequence alignment