Detailed information NTG0223104

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: A6J82_RS01680
• Genome accession: NZ_CP020449
• Coordinates: 290219..291121 (-)
• Length: 300 a.a.
• NCBI ID: WP_000912098.1
• Uniprot ID: A0AAD2WWZ7
• Organism: Streptococcus agalactiae strain FDAARGOS_254
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 285219..296121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J82_RS01660 (A6J82_01680)	-	286181..287959 (-)	1779	WP_001220904.1	acyltransferase family protein	-
A6J82_RS01665 (A6J82_01685)	-	287956..288336 (-)	381	WP_000787702.1	membrane protein	-
A6J82_RS01670 (A6J82_01690)	-	288343..288780 (-)	438	WP_000754818.1	low molecular weight protein-tyrosine-phosphatase	-
A6J82_RS01675 (A6J82_01695)	ruvB	288932..289930 (-)	999	WP_000196633.1	Holliday junction branch migration DNA helicase RuvB	-
A6J82_RS01680 (A6J82_01700)	comR	290219..291121 (-)	903	WP_000912098.1	helix-turn-helix domain-containing protein	Regulator
A6J82_RS01685 (A6J82_01705)	purB	291274..292572 (-)	1299	WP_000572889.1	adenylosuccinate lyase	-
A6J82_RS01690 (A6J82_01710)	-	292569..293378 (-)	810	WP_000982340.1	hypothetical protein	-
A6J82_RS01695 (A6J82_01715)	-	293378..293782 (-)	405	WP_223297811.1	DUF6261 family protein	-
A6J82_RS01700 (A6J82_01720)	-	293749..294120 (-)	372	WP_001872566.1	hypothetical protein	-
A6J82_RS01705 (A6J82_01725)	-	294400..295572 (-)	1173	WP_001248533.1	hypothetical protein	-

Sequence

Protein

• Length: 300 a.a.
• Molecular weight: 35606.08 Da
• Isoelectric Point: 6.5030

>NTDB_id=223104 A6J82_RS01680 WP_000912098.1 290219..291121(-) (comR) [Streptococcus agalactiae strain FDAARGOS_254]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YKLLRTPTYGDANRLAVREAYFDEIYEVFYEELPEDERLIIDCMQSKLDVHFSVNDNFGITILHDYFDQIKKKKEYTTND
FVMIDLYLLCFSINYGMKSLYSLENYHFIMSKLLEQDNLLPEDNFQLNNVLLNHVELAFQFKQKKYVQQIIHRSNAIMTE
IHDFQKRPILSLIEWKYLLIIEKDRTKAETCFKQSILFAELIGDLYLKGKLIEEWNKDLT

Nucleotide

• Length: 903 bp

>NTDB_id=223104 A6J82_RS01680 WP_000912098.1 290219..291121(-) (comR) [Streptococcus agalactiae strain FDAARGOS_254]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TACAAATTGTTGCGTACCCCGACTTACGGAGATGCTAATAGACTTGCAGTTAGAGAAGCATATTTTGATGAAATCTATGA
AGTATTTTATGAGGAGCTCCCAGAAGATGAAAGACTAATTATTGATTGTATGCAATCAAAATTAGATGTTCATTTTTCTG
TTAATGATAATTTTGGAATCACTATTTTACATGACTACTTTGATCAAATTAAGAAAAAAAAGGAATATACCACAAATGAT
TTTGTTATGATAGATTTATATTTACTTTGCTTTTCTATTAACTATGGAATGAAGAGCTTGTATTCTTTAGAGAACTATCA
TTTTATTATGTCAAAATTGTTAGAGCAAGATAATTTACTTCCTGAGGATAATTTTCAATTGAACAACGTTTTATTAAATC
ATGTCGAATTAGCTTTTCAATTTAAGCAGAAAAAATATGTACAGCAAATTATTCATAGAAGTAATGCTATTATGACAGAA
ATCCATGATTTTCAAAAAAGACCAATACTAAGCTTAATAGAGTGGAAATATTTATTAATTATTGAAAAAGATAGAACAAA
AGCAGAAACATGTTTTAAACAATCAATTCTATTTGCAGAGTTAATAGGTGATCTATATTTAAAAGGAAAATTAATAGAGG
AGTGGAATAAAGATTTAACATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-295)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	59.375	96	0.57
comR	Streptococcus mutans UA159	52.174	99.667	0.52
comR	Streptococcus pyogenes MGAS8232	50.166	100	0.503
comR	Streptococcus pyogenes MGAS315	47.667	100	0.477
comR	Streptococcus suis P1/7	40.067	99	0.397
comR	Streptococcus suis 05ZYH33	40.067	99	0.397
comR	Streptococcus suis D9	36.184	100	0.367