Detailed information NTG0222984

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: A6J72_RS02480
• Genome accession: NZ_CP020433
• Coordinates: 505448..507598 (-)
• Length: 716 a.a.
• NCBI ID: WP_082311695.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain FDAARGOS_233
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 500448..512598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J72_RS02455 (A6J72_02445)	-	500793..501482 (+)	690	WP_020998895.1	CPBP family intramembrane glutamic endopeptidase	-
A6J72_RS02460 (A6J72_02450)	comE/blpR	501682..502428 (+)	747	WP_192573667.1	response regulator transcription factor	Regulator
A6J72_RS09830	-	502925..503746 (+)	822	WP_225791037.1	sensor histidine kinase	-
A6J72_RS02470 (A6J72_02460)	-	503827..503979 (-)	153	WP_003073362.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
A6J72_RS02475 (A6J72_02465)	-	504076..505437 (-)	1362	WP_082311694.1	bacteriocin secretion accessory protein	-
A6J72_RS02480 (A6J72_02470)	comA/nlmT	505448..507598 (-)	2151	WP_082311695.1	peptide cleavage/export ABC transporter	Regulator
A6J72_RS02490 (A6J72_02480)	-	508079..508453 (+)	375	WP_003073369.1	hypothetical protein	-
A6J72_RS02495 (A6J72_02485)	-	508526..509131 (-)	606	WP_082311697.1	superoxide dismutase	-
A6J72_RS02500 (A6J72_02490)	holA	509202..510239 (-)	1038	WP_082311698.1	DNA polymerase III subunit delta	-
A6J72_RS02505 (A6J72_02495)	cvfB	510299..511153 (-)	855	WP_082311699.1	RNA-binding virulence regulatory protein CvfB	-
A6J72_RS02510 (A6J72_02500)	frr	511266..511823 (-)	558	WP_020998907.1	ribosome recycling factor	-
A6J72_RS02515 (A6J72_02505)	pyrH	511827..512567 (-)	741	WP_003073377.1	UMP kinase	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80427.01 Da
• Isoelectric Point: 9.3439

>NTDB_id=222984 A6J72_RS02480 WP_082311695.1 505448..507598(-) (comA/nlmT) [Streptococcus intermedius strain FDAARGOS_233]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKGKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLISLIPLI
FKQKMLVTYIVLASLLVTLINIVGSYYLQGILDEYIPNQMRSTLGIVSIGLIITYILQQMMSFSRDYLLIVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSILIIVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEEARYQKIDSEFVNYLDKSFTLSKYSIFQTTLKQGFQLI
LNVLILWLGAHLVISEKISIGQLITFTALLSYFTNSLESIINLQTKLQSAKVANKRLNEVYLVESEFKTKQTLIEKGFLT
GDITFHNVSYKYGFGRDTLSDINLTIKTGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGTNQIFSQKEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHAELMERQGFYHHLFNK

Nucleotide

• Length: 2151 bp

>NTDB_id=222984 A6J72_RS02480 WP_082311695.1 505448..507598(-) (comA/nlmT) [Streptococcus intermedius strain FDAARGOS_233]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGGTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACCAAGATCTCAAAAGAAACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAAAATGGTTTGATAAGCTTAATTCCTCTTATT
TTTAAACAGAAAATGCTGGTCACCTATATTGTTTTAGCTAGTTTGCTTGTGACACTCATCAATATTGTTGGATCTTACTA
TCTACAAGGAATTTTAGATGAATACATTCCAAATCAAATGAGATCAACTCTTGGAATAGTGTCTATTGGTCTGATTATTA
CTTATATTTTGCAGCAAATGATGAGCTTTTCCAGAGATTACTTATTGATTGTACTTAGTCAGCGGCTGACCATCGATGTG
ATTTTATCATATATTCGACACATTTTTGAATTACCAATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTCTATTTTGATAA
TAGTAGGAGGGGTATTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACGGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGCAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACCATTAAATCTTTAACAAGCGAAGAAGCTCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGATAAATCTTTTACGCTTAGTAAATATTCTATTTTTCAAACAACTCTTAAACAAGGCTTTCAATTAATT
TTAAATGTGCTTATTTTATGGCTCGGTGCGCATTTAGTTATATCTGAGAAAATCTCAATTGGGCAGCTCATCACATTTAC
GGCTCTACTTTCTTATTTTACAAATTCTCTTGAAAGTATTATTAATCTGCAAACTAAGCTGCAATCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATTTAGTAGAGTCTGAATTTAAAACTAAGCAAACACTTATAGAGAAAGGTTTCTTGACT
GGTGATATTACGTTCCATAATGTCTCCTATAAATACGGCTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AACAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGACCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCCATCTTAGAAAATCTTACATTAGGGACGAATCAAATATTTTCTCA
AAAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGACGAAGCGACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATGGGTTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGAACAAATCAGGTTATTGTTCTTGATAAAGGGCAGA
TTATTGAAACTGGATCCCACGCTGAATTGATGGAAAGACAAGGCTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (168-437)

• ABC transporter (ABC_tran) (499-648)

• Peptidase C39 family (Peptidase_C39) (6-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.073	99.022	0.714
comA	Streptococcus mitis NCTC 12261	66.76	99.581	0.665
comA	Streptococcus mitis SK321	66.62	99.581	0.663
comA	Streptococcus gordonii str. Challis substr. CH1	66.199	99.581	0.659
comA	Streptococcus pneumoniae D39	66.059	99.581	0.658
comA	Streptococcus pneumoniae R6	66.059	99.581	0.658
comA	Streptococcus pneumoniae Rx1	66.059	99.581	0.658
comA	Streptococcus pneumoniae TIGR4	65.638	99.581	0.654