Detailed information NTG0222921

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: A6J68_RS01030
• Genome accession: NZ_CP020432
• Coordinates: 194675..195904 (+)
• Length: 409 a.a.
• NCBI ID: WP_000728357.1
• Uniprot ID: A0AAD2WWM9
• Organism: Streptococcus sp. 'group B' strain FDAARGOS_229
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 189675..200904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J68_RS01005 (A6J68_01005)	-	190836..193415 (+)	2580	WP_000154442.1	YfhO family protein	-
A6J68_RS01025 (A6J68_01025)	rlmH	193995..194474 (-)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
A6J68_RS01030 (A6J68_01030)	htrA	194675..195904 (+)	1230	WP_000728357.1	S1C family serine protease	Regulator
A6J68_RS01035 (A6J68_01035)	spo0J	196002..196775 (+)	774	WP_000456086.1	ParB/RepB/Spo0J family partition protein	Regulator
A6J68_RS01040 (A6J68_01040)	dnaA	196984..198345 (+)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
A6J68_RS01045 (A6J68_01045)	dnaN	198500..199636 (+)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
A6J68_RS01050 (A6J68_01050)	-	199694..200587 (+)	894	WP_000987442.1	diacylglycerol/lipid kinase family protein	-
A6J68_RS01055 (A6J68_01055)	-	200597..200815 (+)	219	WP_105253154.1	DUF951 domain-containing protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43090.54 Da
• Isoelectric Point: 9.5271

>NTDB_id=222921 A6J68_RS01030 WP_000728357.1 194675..195904(+) (htrA) [Streptococcus sp. 'group B' strain FDAARGOS_229]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=222921 A6J68_RS01030 WP_000728357.1 194675..195904(+) (htrA) [Streptococcus sp. 'group B' strain FDAARGOS_229]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAAGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACGGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGGGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.359	96.088	0.609
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.533	97.311	0.55
htrA	Streptococcus pneumoniae TIGR4	55.037	99.511	0.548
htrA	Streptococcus pneumoniae Rx1	55.037	99.511	0.548
htrA	Streptococcus pneumoniae D39	55.037	99.511	0.548
htrA	Streptococcus pneumoniae R6	55.037	99.511	0.548