Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   A6J31_RS06950 Genome accession   NZ_CP020431
Coordinates   1351692..1352387 (-) Length   231 a.a.
NCBI ID   WP_080610788.1    Uniprot ID   A0A1V0GE76
Organism   Streptococcus sp. FDAARGOS_192     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1346692..1357387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS06935 (A6J31_06865) - 1347503..1348048 (-) 546 WP_013991031.1 GNAT family N-acetyltransferase -
  A6J31_RS06940 (A6J31_06870) - 1348114..1349376 (-) 1263 WP_021143745.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  A6J31_RS06945 (A6J31_06875) - 1349462..1351702 (-) 2241 WP_080610787.1 DNA internalization-related competence protein ComEC/Rec2 -
  A6J31_RS06950 (A6J31_06880) comEA 1351692..1352387 (-) 696 WP_080610788.1 helix-hairpin-helix domain-containing protein Machinery gene
  A6J31_RS06955 (A6J31_06885) - 1352496..1353251 (-) 756 WP_002948862.1 lysophospholipid acyltransferase family protein -
  A6J31_RS06960 (A6J31_06890) - 1353381..1354316 (+) 936 WP_080610789.1 polysaccharide deacetylase family protein -
  A6J31_RS06965 (A6J31_06895) - 1354366..1355130 (+) 765 WP_037599202.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  A6J31_RS06970 (A6J31_06900) - 1355134..1355403 (+) 270 WP_080610790.1 GIY-YIG nuclease family protein -
  A6J31_RS06975 (A6J31_06905) - 1355464..1357050 (-) 1587 WP_004183188.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24393.38 Da        Isoelectric Point: 4.9649

>NTDB_id=222882 A6J31_RS06950 WP_080610788.1 1351692..1352387(-) (comEA) [Streptococcus sp. FDAARGOS_192]
MKEKILAYVKDNRLFVSVIAVLMMIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSKKEK
SKVTVDVKGAVANPGVYTLKASARVTDAIKAAGGMTEDADAKSVNLAASLSDEEVIYVATKDENLSVLGQSGTGQVSDKG
GQTSAKDGKINLNTATSEELQTISGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=222882 A6J31_RS06950 WP_080610788.1 1351692..1352387(-) (comEA) [Streptococcus sp. FDAARGOS_192]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGATGATTTTTTG
CTTCTTTCTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CCTCCTCCTCTAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACTGAAGGAAGTAAAAAGGAGAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGCTAATCCGGGTGTTTATACTTTAAAAGCAAGCGCTAGGGTGACTGA
TGCCATCAAAGCTGCTGGGGGAATGACTGAGGATGCGGATGCTAAGAGTGTTAATTTAGCTGCAAGCCTGTCAGACGAAG
AGGTTATCTATGTGGCAACTAAGGATGAAAACCTTTCTGTTCTTGGTCAATCAGGAACTGGTCAGGTCTCTGACAAAGGA
GGGCAAACTAGTGCTAAGGATGGCAAAATCAACTTAAACACAGCGACTTCAGAGGAGTTACAAACCATTTCTGGAATTGG
CGCTAAGCGTGCTGAGGATATCATTGCCTATCGTGAAAGTCATGGAGGTTTTCAATCCGTAGATGACTTGAAAAATGTCT
CAGGGATTGGTGATAAAACTTTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(168-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GE76

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

92.641

100

0.926
  comEA/celA/cilE Streptococcus mitis SK321

41.048

99.134

0.407
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.912

98.701

0.394
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae D39

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae R6

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus mitis NCTC 12261

38.596

98.701

0.381

Multiple sequence alignment