Detailed information NTG0222869

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: A6J31_RS04730
• Genome accession: NZ_CP020431
• Coordinates: 776292..777131 (-)
• Length: 279 a.a.
• NCBI ID: WP_080610563.1
• Uniprot ID: A0A1V0GD09
• Organism: Streptococcus sp. FDAARGOS_192
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 771292..782131

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J31_RS04710 (A6J31_04665)	-	771754..772239 (-)	486	WP_225791579.1	nisG	-
A6J31_RS04715 (A6J31_04670)	-	772391..773119 (-)	729	WP_225791580.1	lantibiotic ABC transporter permease	-
A6J31_RS04720 (A6J31_04675)	-	773124..773798 (-)	675	WP_080610562.1	ABC transporter ATP-binding protein	-
A6J31_RS04725 (A6J31_04680)	topA	773980..776124 (-)	2145	WP_014633069.1	type I DNA topoisomerase	-
A6J31_RS04730 (A6J31_04685)	dprA	776292..777131 (-)	840	WP_080610563.1	DNA-processing protein DprA	Machinery gene
A6J31_RS04735 (A6J31_04690)	-	777198..778118 (-)	921	WP_080610564.1	ROK family protein	-
A6J31_RS04740 (A6J31_04695)	-	778125..778895 (-)	771	WP_080610565.1	ribonuclease HII	-
A6J31_RS04745 (A6J31_04700)	ylqF	778882..779736 (-)	855	WP_014634567.1	ribosome biogenesis GTPase YlqF	-
A6J31_RS04750 (A6J31_04705)	-	779865..780554 (-)	690	WP_013990509.1	XRE family transcriptional regulator	-
A6J31_RS04755 (A6J31_04710)	-	780649..781164 (-)	516	WP_080610566.1	transcription repressor NadR	-
A6J31_RS04760 (A6J31_04715)	-	781187..781714 (-)	528	WP_002883896.1	ECF transporter S component	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31279.18 Da
• Isoelectric Point: 8.4498

>NTDB_id=222869 A6J31_RS04730 WP_080610563.1 776292..777131(-) (dprA) [Streptococcus sp. FDAARGOS_192]
MNNFELFKLKAAGLTNLNILNILDYQKTQDRKLSLRDMAVVSKSKNAVLFMEKYKSLDIKQLKEQFERFPTLSIFDNEYP
IELKHTYNPPVLLYYQGNLDLLSKPKLAVVGARKCSETGKQSVRKIVSELGNHFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDILSEFS

Nucleotide

• Length: 840 bp

>NTDB_id=222869 A6J31_RS04730 WP_080610563.1 776292..777131(-) (dprA) [Streptococcus sp. FDAARGOS_192]
ATGAATAATTTTGAACTTTTTAAACTTAAAGCCGCTGGGTTGACGAATTTGAATATCTTAAATATTTTGGACTATCAAAA
GACTCAAGATAGAAAATTGAGTTTACGTGATATGGCAGTGGTATCCAAGTCTAAAAATGCCGTTCTTTTTATGGAAAAGT
ATAAGAGTTTAGATATTAAGCAACTCAAAGAACAGTTTGAACGTTTTCCTACGTTATCGATTTTTGATAATGAATATCCC
ATTGAGCTGAAGCATACCTATAATCCTCCTGTCCTCCTTTATTATCAGGGGAATCTTGACTTGCTGAGTAAACCAAAGCT
AGCTGTTGTTGGGGCAAGAAAGTGTTCTGAAACAGGCAAACAGTCCGTTCGAAAAATTGTTAGTGAACTTGGGAATCACT
TTACTATTGTGAGTGGATTGGCGCGTGGGATTGATACTTGTGCGCATATGGAGGCCTTGAAAAATAAGGGGAACACCATT
GCAGTTATCGGGACCGGACTTGATGTTTATTATCCTAAAGAAAATAAAGCTTTGCAGGACTATATGGCCAAAAATCATTT
AGTTCTTACAGAATATGGACCGGGTGAACAGCCTCTCAAGTACCACTTTCCTGAACGCAATCGGATTATTTCTGGATTGT
GTCAAGGAGTTATGGTCGTAGAAGCAAAACTTCGCTCAGGAAGTCTGATTACTTGTGAGCGTGCCATGGAAGAAGGTAGA
GATGTTTTTGCTATTCCAGGAAATATTTTAGATGGAAAATCAGACGGATGCCATCACTTAATTCAAGAGGGCGCAAAGTG
CATTACGACAGGGTTTGACATCCTTTCAGAGTTTTCTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

3D structure

• AlphaFold DB: A0A1V0GD09

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	71.685	100	0.717
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus mitis SK321	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.95	99.642	0.627
dprA	Lactococcus lactis subsp. cremoris KW2	59.712	99.642	0.595
dprA	Latilactobacillus sakei subsp. sakei 23K	40.541	92.832	0.376