Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   A6J31_RS03750 Genome accession   NZ_CP020431
Coordinates   556670..557377 (+) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus sp. FDAARGOS_192     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 551670..562377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS03725 (A6J31_03680) - 552441..553208 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  A6J31_RS03730 (A6J31_03685) - 553396..554046 (-) 651 WP_059749145.1 amino acid ABC transporter permease -
  A6J31_RS03735 (A6J31_03690) - 554058..554756 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  A6J31_RS03740 (A6J31_03695) - 554774..555607 (-) 834 WP_080610472.1 transporter substrate-binding domain-containing protein -
  A6J31_RS03745 (A6J31_03700) - 555617..556384 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  A6J31_RS03750 (A6J31_03705) vicR 556670..557377 (+) 708 WP_002884978.1 response regulator YycF Regulator
  A6J31_RS03755 (A6J31_03710) vicK 557370..558710 (+) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  A6J31_RS03760 (A6J31_03715) vicX 558716..559528 (+) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  A6J31_RS03765 (A6J31_03720) - 559587..559946 (+) 360 WP_037611660.1 YbaN family protein -
  A6J31_RS03770 (A6J31_03725) - 559998..561212 (-) 1215 WP_073689957.1 aminoacyltransferase -
  A6J31_RS03775 (A6J31_03730) yidA 561214..562023 (-) 810 WP_002885000.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=222866 A6J31_RS03750 WP_002884978.1 556670..557377(+) (vicR) [Streptococcus sp. FDAARGOS_192]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=222866 A6J31_RS03750 WP_002884978.1 556670..557377(+) (vicR) [Streptococcus sp. FDAARGOS_192]
ATGAAAAAAATTCTAGTAGTTGATGATGAAAGACCAATCTCGGATATCATCAAGTTTAATCTGACTAAAGAGGGTTATGA
AGTGGTTACGGCTTTTGATGGTCGTGAAGCTTTAGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGCTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCAATTATCATGCTCTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGACTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTGCTTGAAAC
TGTTTGGGGCTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACAATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment