Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   A6J31_RS03755 Genome accession   NZ_CP020431
Coordinates   557370..558710 (+) Length   446 a.a.
NCBI ID   WP_002885062.1    Uniprot ID   A0A0F3HCD0
Organism   Streptococcus sp. FDAARGOS_192     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 552370..563710
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS03725 (A6J31_03680) - 552441..553208 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  A6J31_RS03730 (A6J31_03685) - 553396..554046 (-) 651 WP_059749145.1 amino acid ABC transporter permease -
  A6J31_RS03735 (A6J31_03690) - 554058..554756 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  A6J31_RS03740 (A6J31_03695) - 554774..555607 (-) 834 WP_080610472.1 transporter substrate-binding domain-containing protein -
  A6J31_RS03745 (A6J31_03700) - 555617..556384 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  A6J31_RS03750 (A6J31_03705) vicR 556670..557377 (+) 708 WP_002884978.1 response regulator YycF Regulator
  A6J31_RS03755 (A6J31_03710) vicK 557370..558710 (+) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  A6J31_RS03760 (A6J31_03715) vicX 558716..559528 (+) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  A6J31_RS03765 (A6J31_03720) - 559587..559946 (+) 360 WP_037611660.1 YbaN family protein -
  A6J31_RS03770 (A6J31_03725) - 559998..561212 (-) 1215 WP_073689957.1 aminoacyltransferase -
  A6J31_RS03775 (A6J31_03730) yidA 561214..562023 (-) 810 WP_002885000.1 sugar-phosphatase -
  A6J31_RS03780 (A6J31_03735) - 562201..563067 (+) 867 WP_021144255.1 GNAT family N-acetyltransferase -
  A6J31_RS03785 (A6J31_03740) - 563150..563536 (+) 387 WP_002884910.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50945.21 Da        Isoelectric Point: 5.1606

>NTDB_id=222867 A6J31_RS03755 WP_002885062.1 557370..558710(+) (vicK) [Streptococcus sp. FDAARGOS_192]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDYETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=222867 A6J31_RS03755 WP_002885062.1 557370..558710(+) (vicK) [Streptococcus sp. FDAARGOS_192]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTATTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTTTCTTACATGAGTGATGGGGTTAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTATGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAATTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCACGATGCCACTGAGCAAGAAAAAGAAGAGCGTGAACGTCGACTCTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGACGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGATCTCTTGGCACT
GTCACGTATTGACAATAAGAGTACCCAACTTGATGTTGAGATGACTAATTTCACAGCCTTCATGACCTATATCTTGAATC
GTTTTGACCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGAGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACTCAGGTCGTGGATAATATTCTTAATAATGCCATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGACTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGAACTGGTCTA
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F3HCD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657

Multiple sequence alignment