Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C2H97_RS08565 Genome accession   NZ_CP026038
Coordinates   1641676..1642878 (-) Length   400 a.a.
NCBI ID   WP_120027674.1    Uniprot ID   -
Organism   Bacillus subtilis PY79 strain PK1_3     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1636676..1647878
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H97_RS08540 (C2H97_08570) rocE 1636782..1638185 (-) 1404 WP_120027671.1 amino acid permease -
  C2H97_RS08545 (C2H97_08575) rocD 1638408..1639613 (-) 1206 WP_120027672.1 ornithine aminotransferase -
  C2H97_RS08550 (C2H97_08580) rocR 1639854..1641239 (+) 1386 WP_120027673.1 arginine utilization regulatory protein RocR -
  C2H97_RS08555 (C2H97_08585) - 1641221..1641409 (-) 189 Protein_1684 ATP-binding protein -
  C2H97_RS08560 - 1641526..1641656 (-) 131 Protein_1685 hypothetical protein -
  C2H97_RS08565 (C2H97_08595) htrA 1641676..1642878 (-) 1203 WP_120027674.1 serine protease HtrC Regulator
  C2H97_RS08570 (C2H97_08600) vicX 1642960..1643754 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  C2H97_RS08575 (C2H97_08605) walI 1643776..1644618 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  C2H97_RS08580 (C2H97_08610) walH 1644605..1645972 (-) 1368 WP_046664054.1 WalRK two-component regulatory system regulator WalH -
  C2H97_RS08585 (C2H97_08615) walK 1645962..1647797 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42810.63 Da        Isoelectric Point: 5.7904

>NTDB_id=222797 C2H97_RS08565 WP_120027674.1 1641676..1642878(-) (htrA) [Bacillus subtilis PY79 strain PK1_3]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRKVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRISAELVGSDQLMDL
AVLRVKSNKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=222797 C2H97_RS08565 WP_120027674.1 1641676..1642878(-) (htrA) [Bacillus subtilis PY79 strain PK1_3]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGAAGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGATGGCTCACGAATATCAGCTGAACTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCAATAAAATTAAAGCAGTCGCAGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAATCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(200-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus gordonii str. Challis substr. CH1

41.045

100

0.413
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373

Multiple sequence alignment