Detailed information NTG0220916

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: B5D85_RS05025
• Genome accession: NZ_CP020082
• Coordinates: 935514..936350 (+)
• Length: 278 a.a.
• NCBI ID: WP_076639652.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain STAB120304
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 930514..941350

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B5D85_RS04995 (B5D85_04975)	-	930996..931436 (+)	441	WP_009880949.1	hypothetical protein	-
B5D85_RS05000 (B5D85_04980)	-	931486..932397 (-)	912	WP_076639650.1	diacylglycerol/lipid kinase family protein	-
B5D85_RS05005 (B5D85_04985)	trhA	932514..933164 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
B5D85_RS05010 (B5D85_04990)	-	933161..933601 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
B5D85_RS05015 (B5D85_04995)	ylqF	933820..934668 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
B5D85_RS05020 (B5D85_05000)	-	934658..935449 (+)	792	WP_076639651.1	ribonuclease HII	-
B5D85_RS05025 (B5D85_05005)	dprA	935514..936350 (+)	837	WP_076639652.1	DNA-processing protein DprA	Machinery gene
B5D85_RS05030 (B5D85_05010)	topA	936457..938586 (+)	2130	WP_076639653.1	type I DNA topoisomerase	-
B5D85_RS09945	-	938661..939545 (-)	885	Protein_929	LysR family transcriptional regulator	-
B5D85_RS05045 (B5D85_05025)	-	939558..940124 (+)	567	Protein_930	PTS sugar transporter subunit IIC	-
B5D85_RS05050 (B5D85_05030)	-	940139..941091 (+)	953	Protein_931	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30978.99 Da
• Isoelectric Point: 9.2511

>NTDB_id=220916 B5D85_RS05025 WP_076639652.1 935514..936350(+) (dprA) [Streptococcus pyogenes strain STAB120304]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=220916 B5D85_RS05025 WP_076639652.1 935514..936350(+) (dprA) [Streptococcus pyogenes strain STAB120304]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCACCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363