Detailed information NTG0220430

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: B4W66_RS04665
• Genome accession: NZ_CP020027
• Coordinates: 891240..892076 (+)
• Length: 278 a.a.
• NCBI ID: WP_076639652.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain STAB090229
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 886240..897076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B4W66_RS04635 (B4W66_04635)	-	886722..887162 (+)	441	WP_009880949.1	hypothetical protein	-
B4W66_RS04640 (B4W66_04640)	-	887212..888123 (-)	912	WP_076639650.1	diacylglycerol/lipid kinase family protein	-
B4W66_RS04645 (B4W66_04645)	trhA	888240..888890 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
B4W66_RS04650 (B4W66_04650)	-	888887..889327 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
B4W66_RS04655 (B4W66_04655)	ylqF	889546..890394 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
B4W66_RS04660 (B4W66_04660)	-	890384..891175 (+)	792	WP_076639651.1	ribonuclease HII	-
B4W66_RS04665 (B4W66_04665)	dprA	891240..892076 (+)	837	WP_076639652.1	DNA-processing protein DprA	Machinery gene
B4W66_RS04670 (B4W66_04670)	topA	892183..894312 (+)	2130	WP_076639653.1	type I DNA topoisomerase	-
B4W66_RS09545	-	894387..895271 (-)	885	Protein_867	LysR family transcriptional regulator	-
B4W66_RS04685 (B4W66_04685)	-	895284..895850 (+)	567	Protein_868	PTS sugar transporter subunit IIC	-
B4W66_RS04690 (B4W66_04690)	-	895865..896817 (+)	953	Protein_869	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30978.99 Da
• Isoelectric Point: 9.2511

>NTDB_id=220430 B4W66_RS04665 WP_076639652.1 891240..892076(+) (dprA) [Streptococcus pyogenes strain STAB090229]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=220430 B4W66_RS04665 WP_076639652.1 891240..892076(+) (dprA) [Streptococcus pyogenes strain STAB090229]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCACCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363