Detailed information NTG0219007

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SPSF3K_RS10565
• Genome accession: NZ_CP025420
• Coordinates: 2073290..2074207 (-)
• Length: 305 a.a.
• NCBI ID: WP_003107457.1
• Uniprot ID: A0ABP2SVA0
• Organism: Streptococcus parauberis strain SPOF3K
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 2068290..2079207

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPSF3K_RS10545 (SPSF3K_02134)	-	2069136..2070914 (-)	1779	WP_003107454.1	acyltransferase family protein	-
SPSF3K_RS10550 (SPSF3K_02135)	-	2070911..2071312 (-)	402	WP_003105881.1	membrane protein	-
SPSF3K_RS10555 (SPSF3K_02136)	-	2071341..2071769 (-)	429	WP_003107455.1	low molecular weight protein-tyrosine-phosphatase	-
SPSF3K_RS10560 (SPSF3K_02137)	ruvB	2071993..2072991 (-)	999	WP_003105437.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
SPSF3K_RS11250 (SPSF3K_02138)	-	2073126..2073224 (-)	99	WP_199764314.1	quorum-sensing system DWW-type pheromone	-
SPSF3K_RS10565 (SPSF3K_02139)	comR	2073290..2074207 (-)	918	WP_003107457.1	helix-turn-helix transcriptional regulator	Regulator
SPSF3K_RS10570 (SPSF3K_02140)	purB	2074324..2075616 (-)	1293	WP_003108970.1	adenylosuccinate lyase	-
SPSF3K_RS10575 (SPSF3K_02141)	purK	2075626..2076711 (-)	1086	WP_003108971.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SPSF3K_RS10580 (SPSF3K_02142)	purE	2076698..2077186 (-)	489	WP_003107462.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SPSF3K_RS10585 (SPSF3K_02143)	purD	2077394..2078656 (-)	1263	WP_003108972.1	phosphoribosylamine--glycine ligase	-

Sequence

Protein

• Length: 305 a.a.
• Molecular weight: 35766.83 Da
• Isoelectric Point: 9.0707

>NTDB_id=219007 SPSF3K_RS10565 WP_003107457.1 2073290..2074207(-) (comR) [Streptococcus parauberis strain SPOF3K]
MPELGDKIKAIRLGKKLTRESICGDETELSVRQLVRIEQNQSLPTLAKLVYLAKVLDIRLDKLINPKTISIPHDYLALKY
QIIRTPLYMNDQVMAIREGQFDAIFEKYYDYLPDEEKLIIDFLQSKFDVYQSGDANFGRPLLQDYIRQISKKKRYQINDI
FLIDLYLTCAIVSSFKAEFFDLDLYRRFLSKLLLMEKTLALSDLFLLNNVLLTCIDVGIRIGHFEVIQPALKASHRIMYK
VQDFQRLPIYCMHAWKNALFYTKSVKRGEDYFHQAQLFAKLIGDKNLEGKLAREWQKNLAESEKT

Nucleotide

• Length: 918 bp

>NTDB_id=219007 SPSF3K_RS10565 WP_003107457.1 2073290..2074207(-) (comR) [Streptococcus parauberis strain SPOF3K]
ATGCCAGAGCTCGGGGATAAAATCAAAGCTATTCGACTGGGAAAAAAGTTAACTAGAGAGTCTATTTGCGGTGATGAGAC
AGAATTGTCTGTGCGTCAATTGGTACGAATTGAGCAAAATCAATCTCTGCCTACTCTTGCAAAATTAGTTTATCTTGCTA
AAGTTCTAGATATTAGACTTGATAAGTTAATTAACCCAAAAACAATTTCAATCCCACATGATTATCTTGCCCTTAAATAT
CAAATTATCCGGACACCGTTGTATATGAATGATCAAGTTATGGCAATTAGAGAAGGGCAGTTTGATGCTATTTTTGAAAA
GTACTATGACTATTTGCCAGATGAAGAAAAACTCATTATTGATTTTTTACAATCTAAATTTGATGTCTATCAAAGTGGAG
ATGCAAATTTTGGCCGTCCCCTCTTACAAGATTACATCAGACAAATCAGTAAGAAAAAACGCTATCAAATTAATGATATC
TTCTTAATTGATCTCTATTTAACCTGTGCGATTGTCAGTTCTTTTAAAGCTGAGTTTTTTGACTTGGACCTTTATCGTCG
CTTTCTGTCCAAGTTATTGTTAATGGAGAAGACATTAGCCTTAAGTGATTTATTCTTACTTAATAATGTCCTTTTAACCT
GTATTGATGTTGGTATTAGGATAGGTCATTTTGAAGTCATTCAACCGGCTTTAAAGGCAAGTCATCGCATTATGTACAAG
GTTCAAGATTTCCAACGCCTGCCAATTTACTGCATGCATGCCTGGAAAAATGCTCTTTTTTATACTAAGTCTGTAAAAAG
AGGAGAGGATTACTTTCATCAGGCGCAGCTATTTGCCAAATTGATTGGTGATAAAAATTTGGAAGGGAAATTAGCTCGTG
AATGGCAAAAAAATTTGGCAGAAAGTGAAAAAACATGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (72-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	45.819	98.033	0.449
comR	Streptococcus mutans UA159	42.617	97.705	0.416
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	43.902	94.098	0.413
comR	Streptococcus pyogenes MGAS8232	39.799	98.033	0.39
comR	Streptococcus suis P1/7	37.374	97.377	0.364
comR	Streptococcus suis 05ZYH33	37.374	97.377	0.364