Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   BWR56_RS09625 Genome accession   NZ_CP019562
Coordinates   1932069..1934222 (-) Length   717 a.a.
NCBI ID   WP_061421733.1    Uniprot ID   -
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1927069..1939222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS09615 (BWR56_1903) purC 1929831..1930538 (-) 708 WP_139658205.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  BWR56_RS09620 (BWR56_1904) comB 1930707..1932056 (-) 1350 WP_071852016.1 competence pheromone export protein ComB Regulator
  BWR56_RS09625 (BWR56_1905) comA 1932069..1934222 (-) 2154 WP_061421733.1 peptide cleavage/export ABC transporter ComA Regulator
  BWR56_RS09630 (BWR56_1906) - 1934385..1934579 (-) 195 WP_049506282.1 hypothetical protein -
  BWR56_RS10030 - 1934905..1935072 (-) 168 WP_231071383.1 bacteriocin immunity protein -
  BWR56_RS09645 (BWR56_1907) - 1935139..1935327 (-) 189 WP_000722238.1 hypothetical protein -
  BWR56_RS09650 (BWR56_1908) - 1935337..1935504 (-) 168 WP_000415691.1 bacteriocin -
  BWR56_RS09655 (BWR56_1909) - 1935522..1935710 (-) 189 WP_049506287.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  BWR56_RS09660 (BWR56_1910) - 1936154..1936390 (-) 237 WP_000136435.1 acyl carrier protein -
  BWR56_RS09665 (BWR56_1911) plsX 1936396..1937388 (-) 993 WP_049506288.1 phosphate acyltransferase PlsX -
  BWR56_RS09670 (BWR56_1912) recO 1937385..1938155 (-) 771 WP_000616142.1 DNA repair protein RecO -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80437.75 Da        Isoelectric Point: 7.3722

>NTDB_id=216355 BWR56_RS09625 WP_061421733.1 1932069..1934222(-) (comA) [Streptococcus oralis strain S.MIT/ORALIS-351]
MKFRKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFNLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKKHIHIADPDPGVKLTKISRERFAQEWTGVSIFMAPSPGYKPHKEKKQGLLSFLPI
LLKQRGLITNIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWLGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEQKTVEDLSMM
KGDMTFKQVHYKYGYGRDVLSDINLTIPQGSKMAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLEQGKIVEEGKHADLLAQDGFYAHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=216355 BWR56_RS09625 WP_061421733.1 1932069..1934222(-) (comA) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGAAATTTAGGAAAAGGCACTATCGTCCCCAGGTGGATCAGATGGATTGTGGCGTGGCTTCCTTGGCTATGGTATTTGG
CTACTACGGTAGTTATTACTCCTTGGCTCATCTACGAGAATTAGCCAAGACGACTATGGATGGGACGACCGCTTTGGGAC
TTGTAAAGGTGGCAGAGGAGATTGGGTTTGAGACGCGGGCTATCAAGGCGGATATGACGCTTTTTAATCTGCCAGATTTG
ACCTTTCCTTTTGTGGCCCATGTGCTCAAGGAAGGGAAGTTACTCCACTACTATGTGGTGACAGGTCAGGATAAAAAGCA
CATTCATATCGCTGATCCGGATCCTGGTGTCAAGCTGACCAAGATTTCCCGTGAGCGTTTTGCGCAAGAGTGGACAGGGG
TCAGTATTTTTATGGCGCCATCTCCGGGCTATAAACCTCATAAGGAGAAGAAACAGGGTCTCCTATCCTTCTTGCCAATC
TTACTCAAACAGCGTGGCTTAATTACCAATATCGTCCTAGCGACACTCTTGGTGACCTTGATTAATATTGTGGGCTCCTA
CTATCTTCAGTCTATCATTGACAGTTACGTACCAGACCAGATGCGTTCGACCTTGGGCATTATCTCTATTGGTTTGGTCA
TCGTCTATATTCTCCAGCAGATTTTGTCTTATGCGCAGGAATACCTCTTACTTGTTCTGGGTCAACGGTTGTCCATCGAT
GTGATTTTGTCCTACATCAAGCATGTTTTTCATCTGCCGATGTCCTTTTTCGCGACACGCAGGACAGGAGAAATCGTTTC
TCGTTTTACAGATGCCAATAGTATCATCGATGCACTGGCGTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTGGTCTTGTTTTCACAAAATATGACACTTTTTTTCATTAGTCTACTTGCGCTTCCCATCTATACAGTG
ATTATCTTTGCTTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCTAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAACGGCATTGAGACCATTAAATCTTTGACCAGTGAAAGTTCGCGCTATCAAAAAATTGATAAGGAAT
TTGTGGCTTATCTGAAAAAATCTTTCACCTATAGTCGGGCAGAAAGCCAGCAAAAGGCTCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGCTGGGAGCTATTCTGGTCATGGATGGGAAAATGAGTTTGGGCCAGCTGATTACCTA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATTAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGCAGAAAACAGTCGAAGATTTGAGCATGATG
AAAGGGGATATGACCTTTAAACAAGTTCACTATAAGTATGGCTATGGGCGTGACGTCTTGTCGGATATCAATTTGACCAT
TCCCCAAGGGTCTAAGATGGCTTTTGTGGGGATTTCAGGGTCAGGTAAGACGACCTTGGCCAAGATGATGGTTAATTTCT
ACGATCCTAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGACAAAAAGGCCTTGCGCCAGTATATC
AACTACCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACAAC
TCAAGAGGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGGGAGGATATTGAGCGCATGCCCCTGAATTACCAGACAG
AATTAACTTCGGATGGGGCTGGAATTTCTGGTGGGCAACGGCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACGGATGCA
CCTGTCTTGATCTTGGACGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATCGTGGATAATCTCATGGCTTT
GGACAAGACCTTGATTTTCATTGCTCACCGCTTGACCATTGCTGAGCGGACAGAAAAGGTTGTTGTTTTGGAGCAGGGCA
AGATTGTCGAAGAAGGAAAGCATGCTGATTTGCTTGCACAGGATGGATTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

94.7

100

0.947
  comA Streptococcus pneumoniae Rx1

94.561

100

0.946
  comA Streptococcus pneumoniae D39

94.561

100

0.946
  comA Streptococcus pneumoniae R6

94.561

100

0.946
  comA Streptococcus mitis SK321

94.421

100

0.944
  comA Streptococcus pneumoniae TIGR4

94.142

100

0.941
  comA Streptococcus gordonii str. Challis substr. CH1

80.614

100

0.806
  comA/nlmT Streptococcus mutans UA159

64.435

100

0.644

Multiple sequence alignment