Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   BWR56_RS09620 Genome accession   NZ_CP019562
Coordinates   1930707..1932056 (-) Length   449 a.a.
NCBI ID   WP_071852016.1    Uniprot ID   -
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1925707..1937056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS09605 (BWR56_1902) - 1925893..1929618 (-) 3726 WP_076984870.1 phosphoribosylformylglycinamidine synthase -
  BWR56_RS09615 (BWR56_1903) purC 1929831..1930538 (-) 708 WP_139658205.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  BWR56_RS09620 (BWR56_1904) comB 1930707..1932056 (-) 1350 WP_071852016.1 competence pheromone export protein ComB Regulator
  BWR56_RS09625 (BWR56_1905) comA 1932069..1934222 (-) 2154 WP_061421733.1 peptide cleavage/export ABC transporter ComA Regulator
  BWR56_RS09630 (BWR56_1906) - 1934385..1934579 (-) 195 WP_049506282.1 hypothetical protein -
  BWR56_RS10030 - 1934905..1935072 (-) 168 WP_231071383.1 bacteriocin immunity protein -
  BWR56_RS09645 (BWR56_1907) - 1935139..1935327 (-) 189 WP_000722238.1 hypothetical protein -
  BWR56_RS09650 (BWR56_1908) - 1935337..1935504 (-) 168 WP_000415691.1 bacteriocin -
  BWR56_RS09655 (BWR56_1909) - 1935522..1935710 (-) 189 WP_049506287.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  BWR56_RS09660 (BWR56_1910) - 1936154..1936390 (-) 237 WP_000136435.1 acyl carrier protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49905.84 Da        Isoelectric Point: 5.2449

>NTDB_id=216354 BWR56_RS09620 WP_071852016.1 1930707..1932056(-) (comB) [Streptococcus oralis strain S.MIT/ORALIS-351]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGELLVQYQQGAEAVQIEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIEKGDQLDSQNPAYSFYQTYKNQGEEDPHAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAHATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEQ
GNFFKIEAETNLTSEQAATLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=216354 BWR56_RS09620 WP_071852016.1 1930707..1932056(-) (comB) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGCTCGTATTTCTGTTAGGATTTGCAGTTTTTGCAGAGAAGGAGATTAGTTTGTCTACCAGAGCGACTGTCG
AACCTAGTCGGATTATTGCCAATATCCAGTCGACTAGCAATCAACGCATTGTGGCCAATTATCTGGAAGAAAACAAGTTG
GTCAAGCAGGGGGAACTACTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGATTGAGGCATATGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGATATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTCCCAGAGGCGG
ATAAGTTTGGTTACCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGGAGTAATGTTTCTCAGCAAAAT
GCCAGCATCTCTTCTCAAAATGCGGCAGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGCCAAACAGAGGATAA
AATTCGAGACTACAAAACAGCTAAGTCAGCGATTGAAAAGGGAGATCAACTAGATAGTCAGAATCCAGCCTACTCTTTTT
ATCAGACCTATAAAAATCAAGGTGAAGAAGATCCGCACGCTAAATCGCAAGTTATTGCGCAAGTGGATGCACAAATTGCC
CAGCTAGAGTCCAGTCTAGCTACCTATCGTGTACAGTATGCGGGTTCTGGGGCTCAGCAGGCCCACGCAACGGGACTGGA
TAGTCAACTGGAATCACTTAAATCTCAGCACCTAGTCAAAGTTGGTCAGGAATTAACTCTTCTAGATCAGAAAATTTTGG
AGGCGGAATCGGGTAAGAAGGTACAGGGAGGTCTCCTAGATAAAGGGAAGATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAAACCAGTGATTCTACCATGGTCGCAGAAGGAACCCTGCTAGCCCAACTCTATCCATCCCTGGAAAAAGA
AGGGAAAACCAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCTAGAGTCAAGATTGGGGACTCTGTCCGTTATACTA
CGACTAATGATGCGAAGAATCAAATTTTCCTGGATTCCACGATTACAAGTATTGATGCGACAGCTACAAAGACTGAACAA
GGAAATTTCTTTAAAATTGAGGCGGAGACTAATTTAACTTCGGAGCAGGCTGCAACACTTCGCTATGGTTTAGAAGGCCG
CCTGCAGATGATCACAGGGAAGAAAAGCTATCTCCGTTATTTTTGGGATCAATTTTTGAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

84.152

99.777

0.84
  comB Streptococcus pneumoniae Rx1

82.812

99.777

0.826
  comB Streptococcus pneumoniae D39

82.812

99.777

0.826
  comB Streptococcus pneumoniae R6

82.812

99.777

0.826
  comB Streptococcus mitis NCTC 12261

82.812

99.777

0.826
  comB Streptococcus pneumoniae TIGR4

82.366

99.777

0.822
  comB Streptococcus gordonii str. Challis substr. CH1

55.531

100

0.559

Multiple sequence alignment