Detailed information NTG0216325

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: BWR56_RS05275
• Genome accession: NZ_CP019562
• Coordinates: 1086770..1087618 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705328.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain S.MIT/ORALIS-351
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1081770..1092618

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BWR56_RS05255 (BWR56_1042)	-	1082673..1083329 (-)	657	WP_076984586.1	MmcQ/YjbR family DNA-binding protein	-
BWR56_RS05260 (BWR56_1043)	-	1083373..1084005 (-)	633	WP_076984587.1	copper homeostasis protein CutC	-
BWR56_RS05265 (BWR56_1044)	-	1084099..1084458 (-)	360	WP_001220358.1	YbaN family protein	-
BWR56_RS05270 (BWR56_1045)	topA	1084565..1086652 (-)	2088	WP_000179670.1	type I DNA topoisomerase	-
BWR56_RS05275 (BWR56_1046)	dprA/cilB/dalA	1086770..1087618 (-)	849	WP_000705328.1	DNA-processing protein DprA	Machinery gene
BWR56_RS05280 (BWR56_1047)	-	1087699..1088322 (-)	624	WP_000734769.1	hypothetical protein	-
BWR56_RS05285 (BWR56_1048)	lepA	1088463..1090286 (-)	1824	WP_049505907.1	translation elongation factor 4	-
BWR56_RS05290 (BWR56_1049)	-	1090365..1091093 (-)	729	WP_049505909.1	metallophosphoesterase family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31245.73 Da
• Isoelectric Point: 5.2027

>NTDB_id=216325 BWR56_RS05275 WP_000705328.1 1086770..1087618(-) (dprA/cilB/dalA) [Streptococcus oralis strain S.MIT/ORALIS-351]
MKITNYEIYKLRKAGLSNQQILTVLEYDETVDQELLLGDIAEISGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRSCSSQGAKSVQKVIQGLENELIVVSGLAKGIDTAAHMAALQNGGR
TIAVIGTGLDVFYPRANKRLQEHIGNHHLVLSEYGPGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDVFAIPGNILDGHSDGCHHLIQEGAKLISSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=216325 BWR56_RS05275 WP_000705328.1 1086770..1087618(-) (dprA/cilB/dalA) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGAAGATCACAAACTATGAAATTTACAAATTGAGAAAAGCTGGGCTGAGCAATCAACAAATTTTAACAGTTCTTGAATA
CGATGAGACTGTAGATCAGGAGCTCTTGCTAGGTGATATTGCAGAAATATCTGGGTGTCGTAATCCTGCTGTCTTTATGG
AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAGGAGTTTCAGAAATTTCCATCCTTTTCTATTCTTGATGACTGT
TATCCTTGGGATCTGAGTGAGATTTATGATGCTCCAGTGCTCTTGTTTTATAAAGGAAATCTAGACCTGTTGAAATTTCC
AAAGGTTGCTGTTGTAGGGAGTCGTTCATGTTCTAGTCAGGGAGCAAAATCGGTTCAGAAAGTCATTCAAGGTTTGGAAA
ACGAGTTAATCGTTGTCAGTGGTTTAGCCAAAGGGATTGATACAGCTGCCCATATGGCTGCACTCCAGAATGGAGGAAGA
ACGATTGCCGTCATTGGAACAGGATTGGATGTTTTTTATCCCCGAGCCAATAAACGTTTGCAGGAACACATTGGCAATCA
CCATTTGGTACTTAGCGAGTACGGACCTGGTGAAGAACCCTTGAAATTTCACTTTCCAGCTCGTAATCGCATCATTGCTG
GCCTTTGCCGTGGCGTTATTGTAGCAGAGGCAAGGATGCGTTCTGGTAGTCTTATCACCTGTGAGCGAGCTATGGAGGAA
GGGCGTGATGTTTTTGCCATTCCAGGAAACATTTTAGATGGCCATTCAGATGGCTGTCACCACCTGATCCAAGAGGGAGC
AAAGCTGATTAGCAGTGGACAAGATGTGTTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	91.489	100	0.915
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	91.135	100	0.911
dprA/cilB/dalA	Streptococcus pneumoniae D39	91.135	100	0.911
dprA/cilB/dalA	Streptococcus pneumoniae R6	91.135	100	0.911
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	91.135	100	0.911
dprA/cilB/dalA	Streptococcus mitis SK321	90.426	100	0.904
dprA	Streptococcus mutans UA159	60.714	99.291	0.603
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	99.291	0.543
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362