Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilE   Type   Machinery gene
Locus tag   NMA_RS01390 Genome accession   NC_003116
Coordinates   250476..250988 (-) Length   170 a.a.
NCBI ID   WP_010981065.1    Uniprot ID   P57039
Organism   Neisseria meningitidis Z2491     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 245476..255988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMA_RS01365 (NMA0262) gnd 245992..247440 (-) 1449 WP_002247197.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  NMA_RS01380 (NMA0263) lpxC 248626..249549 (-) 924 WP_002246555.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  NMA_RS01390 (NMA0264) pilE 250476..250988 (-) 513 WP_010981065.1 pilin Machinery gene
  NMA_RS01395 (NMA0265) - 252156..252548 (-) 393 Protein_251 pilin -
  NMA_RS01400 (NMA0266) - 252682..253110 (-) 429 Protein_252 pilin -
  NMA_RS01405 (NMA0267) - 253273..253650 (-) 378 Protein_253 pilin -
  NMA_RS01410 (NMA0268) - 254404..254817 (-) 414 Protein_254 pilin -
  NMA_RS01415 (NMA0269) pilE 255227..255661 (-) 435 WP_173024106.1 pilin Machinery gene

Sequence

Protein


Download         Length: 170 a.a.        Molecular weight: 18134.49 Da        Isoelectric Point: 8.4550

>NTDB_id=21625 NMA_RS01390 WP_010981065.1 250476..250988(-) (pilE) [Neisseria meningitidis Z2491]
MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGEWPSNNTSAGVASSTDIK
GKYVQSVEVKNGVVTATMASSNVNNEIKGKKLSLWAKRQDGSVKWFCGQPVKRNDTATTNDDVKADTAANGKQIDTKHLP
STCRDAASAG

Nucleotide


Download         Length: 513 bp        

>NTDB_id=21625 NMA_RS01390 WP_010981065.1 250476..250988(-) (pilE) [Neisseria meningitidis Z2491]
ATGAACACCCTTCAAAAAGGTTTTACCCTTATCGAGCTGATGATTGTGATTGCCATCGTCGGCATTTTGGCGGCAGTCGC
CCTTCCTGCTTATCAAGACTACACAGCCCGCGCACAAGTTTCCGAAGCCATTCTTTTAGCCGAAGGTCAAAAATCAGCCG
TCACCGAGTATTACCTGAATCACGGCGAATGGCCCAGCAACAACACTTCTGCCGGCGTGGCATCCTCCACCGACATTAAA
GGCAAATATGTTCAAAGCGTTGAAGTCAAAAACGGCGTCGTTACCGCCACAATGGCTTCAAGCAACGTAAACAACGAAAT
CAAAGGCAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTAAGCGCA
ACGACACCGCCACCACCAACGACGACGTCAAAGCCGACACCGCCGCCAACGGCAAGCAGATCGACACCAAGCACCTGCCG
TCAACCTGCCGCGACGCAGCATCTGCCGGATAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)

Pilin (bacterial filament) (Pilin)

(36-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P57039

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae MS11

84.615

99.412

0.841
  pilE Neisseria gonorrhoeae strain FA1090

81.657

99.412

0.812
  pilA/pilA1 Eikenella corrodens VA1

36.517

100

0.382
  comP Acinetobacter baylyi ADP1

37.5

98.824

0.371
  pilE Neisseria elongata subsp. glycolytica ATCC 29315

32.812

100

0.371

Multiple sequence alignment