Detailed information NTG0216243

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: CWQ22_RS00320
• Genome accession: NZ_CP025027
• Coordinates: 44400..45308 (+)
• Length: 302 a.a.
• NCBI ID: WP_000912095.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SGEHI2015-107
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 39400..50308

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWQ22_RS00300 (CWQ22_00300)	purE	39918..40406 (+)	489	WP_001182531.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
CWQ22_RS00305 (CWQ22_00305)	purK	40393..41484 (+)	1092	WP_001084008.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
CWQ22_RS00310 (CWQ22_00310)	-	41536..42927 (+)	1392	WP_001079797.1	hypothetical protein	-
CWQ22_RS00315 (CWQ22_00315)	purB	42949..44247 (+)	1299	WP_000572890.1	adenylosuccinate lyase	-
CWQ22_RS00320 (CWQ22_00320)	comR	44400..45308 (+)	909	WP_000912095.1	XRE family transcriptional regulator	Regulator
CWQ22_RS00325 (CWQ22_00325)	ruvB	45509..46507 (+)	999	WP_000196633.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
CWQ22_RS00330 (CWQ22_00330)	-	46659..47096 (+)	438	WP_000754818.1	low molecular weight protein-tyrosine-phosphatase	-
CWQ22_RS00335 (CWQ22_00335)	-	47103..47483 (+)	381	WP_000787702.1	membrane protein	-
CWQ22_RS00340 (CWQ22_00340)	-	47480..49258 (+)	1779	WP_001220907.1	acyltransferase family protein	-

Sequence

Protein

• Length: 302 a.a.
• Molecular weight: 35727.11 Da
• Isoelectric Point: 5.5329

>NTDB_id=216243 CWQ22_RS00320 WP_000912095.1 44400..45308(+) (comR) [Streptococcus agalactiae strain SGEHI2015-107]
MLKHFGSKVRKFRESQQVTREEFCGDESELSVRQLARIEAGESVPNLSKAHYIARNLGVSLDSLTAGASLELSKKYKELK
YLILRTPTYNDTDRLDLIEKYLDEIYLNFYDDLPEDEKIAIESIQSSLDIYISKSHHFGDDLIREYMNQIKRKKIYSIND
LLIIKLWQYKITASRYDPNIFKIDTFIGTIDKLLNQVKVLSIENLFLLRDVLIYSLGILFILAEYQQIENIINTLNDILI
KTQDFQKRPIIDMFEWKYQLFYKENREVAKRKYQESTLFAQLIGDQVLVTQLKEEWKADYIE

Nucleotide

• Length: 909 bp

>NTDB_id=216243 CWQ22_RS00320 WP_000912095.1 44400..45308(+) (comR) [Streptococcus agalactiae strain SGEHI2015-107]
ATGTTAAAACATTTTGGTAGTAAAGTAAGGAAGTTTAGGGAATCTCAACAGGTGACACGAGAAGAATTTTGTGGCGATGA
ATCAGAGTTATCGGTCCGACAGCTGGCTCGGATTGAAGCAGGAGAATCTGTTCCAAATTTATCTAAGGCGCATTATATCG
CTAGAAATCTAGGAGTTAGTTTAGATTCCTTAACAGCAGGAGCGAGTTTAGAACTGTCAAAAAAATATAAGGAATTAAAG
TATCTTATATTAAGGACGCCTACCTACAATGATACAGATAGACTTGATTTGATTGAAAAATATCTAGATGAGATTTATTT
AAATTTCTATGATGATTTACCTGAAGATGAAAAAATAGCAATTGAGTCCATACAAAGTTCTTTAGATATTTATATTTCTA
AAAGCCATCATTTTGGAGATGACCTGATTAGGGAATACATGAATCAAATTAAACGAAAAAAGATTTACTCTATCAATGAC
TTACTTATAATTAAACTATGGCAATATAAGATTACTGCTAGCAGGTATGATCCCAATATTTTTAAAATAGATACATTTAT
TGGTACTATAGATAAGTTGCTTAATCAAGTAAAGGTATTATCAATTGAAAACCTGTTTTTATTAAGGGATGTCCTCATTT
ATTCGTTAGGTATATTGTTTATATTAGCTGAATATCAGCAAATAGAAAATATAATAAATACTCTAAATGATATTTTAATA
AAAACTCAGGATTTTCAAAAGAGGCCAATAATAGATATGTTCGAATGGAAATATCAGTTGTTTTATAAAGAAAATAGGGA
AGTGGCTAAAAGAAAGTATCAGGAATCAACTCTTTTTGCTCAATTAATTGGCGATCAAGTTTTAGTTACACAGCTAAAAG
AGGAATGGAAAGCAGACTATATAGAATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (74-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	45.151	99.007	0.447
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.296	95.033	0.43
comR	Streptococcus pyogenes MGAS315	43.478	99.007	0.43
comR	Streptococcus pyogenes MGAS8232	41.914	100	0.421
comR	Streptococcus suis P1/7	42.424	98.344	0.417
comR	Streptococcus suis 05ZYH33	42.424	98.344	0.417
comR	Streptococcus suis D9	38.384	98.344	0.377