Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   CVO91_RS02550 Genome accession   NZ_CP024974
Coordinates   478263..480257 (+) Length   664 a.a.
NCBI ID   WP_004195191.1    Uniprot ID   -
Organism   Streptococcus suis strain CZ130302     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 473263..485257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS02535 (CVO91_02535) fmt 475250..476188 (+) 939 WP_100664741.1 methionyl-tRNA formyltransferase -
  CVO91_RS02540 (CVO91_02540) rsmB 476175..477488 (+) 1314 WP_100664742.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  CVO91_RS02545 (CVO91_02545) - 477526..478263 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  CVO91_RS02550 (CVO91_02550) stkP/pknB 478263..480257 (+) 1995 WP_004195191.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  CVO91_RS02555 (CVO91_02555) liaF 480582..481241 (+) 660 WP_232503813.1 cell wall-active antibiotics response protein LiaF -
  CVO91_RS02560 (CVO91_02560) - 481238..482254 (+) 1017 WP_004195187.1 sensor histidine kinase -
  CVO91_RS02565 (CVO91_02565) vraR 482226..482867 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  CVO91_RS02570 (CVO91_02570) - 482917..484317 (+) 1401 WP_004195185.1 Cof-type HAD-IIB family hydrolase -
  CVO91_RS02575 (CVO91_02575) - 484319..484690 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71391.99 Da        Isoelectric Point: 6.5352

>NTDB_id=215797 CVO91_RS02550 WP_004195191.1 478263..480257(+) (stkP/pknB) [Streptococcus suis strain CZ130302]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIAAGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAAMVSIPDVTDKDSDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKTQENAAQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANAELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQTLGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGR

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=215797 CVO91_RS02550 WP_004195191.1 478263..480257(+) (stkP/pknB) [Streptococcus suis strain CZ130302]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCCGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGTATTCCCTATGATG
GAGACAGTGCTGTGACGATTGCTCTTCAGCATTTTCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCAAACGTACCT
CAGGCTTTAGAAAATGTTGTACTAAAAGCCACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTATGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAAGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCCCAAGTTTCTGCGACAGAT
AAGGGGCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGGGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTGTCTGGTCAAACTGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGAATTGGAGGCTCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGGGCAAAAATTACCCTTTATGTTTCCAAAGGAGTAGCGCCACAAGT
TGTGCCGAACGTTGTTGGAAAAACTCAGGAGAATGCTGCTCAAATTCTTCAGACAGCAGGCTTCAGTATTGGAACTATTA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCCGTTGCCAATGCAGAGTTGACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCACGTAGTCAATTACAAACGCTAGGCGTCAATGTGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTACTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCGGCACCAGTAGCGATTCCTCAACAGGAAGTTCCACCAGCACAAGTACTTCAACAGATAGCGGACGATAA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-501)

Protein kinase domain (Pkinase)

(12-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

54.383

84.187

0.458
  stkP Streptococcus pneumoniae TIGR4

68.037

65.964

0.449
  stkP Streptococcus pneumoniae D39

67.808

65.964

0.447
  stkP Streptococcus pneumoniae R6

67.808

65.964

0.447
  stkP Streptococcus pneumoniae Rx1

67.58

65.964

0.446
  pknB Streptococcus mutans UA159

54.953

80.572

0.443