Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CVO91_RS02565 Genome accession   NZ_CP024974
Coordinates   482226..482867 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain CZ130302     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 477226..487867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS02545 (CVO91_02545) - 477526..478263 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  CVO91_RS02550 (CVO91_02550) stkP/pknB 478263..480257 (+) 1995 WP_004195191.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  CVO91_RS02555 (CVO91_02555) liaF 480582..481241 (+) 660 WP_232503813.1 cell wall-active antibiotics response protein LiaF -
  CVO91_RS02560 (CVO91_02560) - 481238..482254 (+) 1017 WP_004195187.1 sensor histidine kinase -
  CVO91_RS02565 (CVO91_02565) vraR 482226..482867 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  CVO91_RS02570 (CVO91_02570) - 482917..484317 (+) 1401 WP_004195185.1 Cof-type HAD-IIB family hydrolase -
  CVO91_RS02575 (CVO91_02575) - 484319..484690 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  CVO91_RS02580 (CVO91_02580) cysK 484716..485642 (-) 927 WP_004195182.1 cysteine synthase A -
  CVO91_RS02585 (CVO91_02585) - 485872..487029 (-) 1158 WP_100664743.1 site-specific integrase -
  CVO91_RS02590 (CVO91_02590) - 487204..487638 (-) 435 WP_100664744.1 type II toxin-antitoxin system PemK/MazF family toxin -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=215798 CVO91_RS02565 WP_002937025.1 482226..482867(+) (vraR) [Streptococcus suis strain CZ130302]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=215798 CVO91_RS02565 WP_002937025.1 482226..482867(+) (vraR) [Streptococcus suis strain CZ130302]
ATGAATACGATTCGAGTGATGTTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGTTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCTCTAAAAACTGTTAAAACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413