Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SPR_RS02395 Genome accession   NC_003098
Coordinates   473479..475155 (-) Length   558 a.a.
NCBI ID   WP_306423909.1    Uniprot ID   -
Organism   Streptococcus pneumoniae R6     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 468479..480155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPR_RS02365 (spr0461) - 468814..469143 (-) 330 WP_000132569.1 hypothetical protein -
  SPR_RS02370 (spr0462) - 469419..469757 (+) 339 WP_000682124.1 LytTR family DNA-binding domain-containing protein -
  SPR_RS02375 (spr0463) comE/blpR 469762..470499 (+) 738 WP_001219139.1 response regulator transcription factor Regulator
  SPR_RS02380 (spr0464) - 470513..471853 (+) 1341 WP_001017622.1 sensor histidine kinase -
  SPR_RS02385 (spr0465) blpC 471895..472050 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  SPR_RS02390 (spr0466) - 472107..473468 (-) 1362 Protein_465 bacteriocin secretion accessory protein -
  SPR_RS02395 (spr0468) comA/nlmT 473479..475155 (-) 1677 WP_306423909.1 peptide cleavage/export ABC transporter Regulator
  SPR_RS11170 (spr0469) comA/nlmT 475049..475636 (-) 588 WP_001856103.1 cysteine peptidase family C39 domain-containing protein Regulator
  SPR_RS02400 (spr0470) - 475926..476159 (+) 234 WP_001093273.1 hypothetical protein -
  SPR_RS02405 (spr0472) - 476191..476880 (+) 690 WP_000760523.1 CPBP family intramembrane glutamic endopeptidase -
  SPR_RS02410 (spr0473) blpZ 476922..477155 (+) 234 WP_000276498.1 immunity protein BlpZ -
  SPR_RS02415 (spr0474) - 477306..477917 (+) 612 WP_000394036.1 CPBP family intramembrane glutamic endopeptidase -
  SPR_RS02420 (spr0475) ccrZ 478078..478872 (+) 795 WP_000363002.1 cell cycle regulator CcrZ -
  SPR_RS02425 (spr0476) trmB 478869..479504 (+) 636 WP_001266083.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  SPR_RS02430 (spr0477) rimP 479630..480109 (+) 480 WP_001810863.1 ribosome maturation factor RimP -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62978.29 Da        Isoelectric Point: 7.1280

>NTDB_id=21547 SPR_RS02395 WP_306423909.1 473479..475155(-) (comA/nlmT) [Streptococcus pneumoniae R6]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=21547 SPR_RS02395 WP_306423909.1 473479..475155(-) (comA/nlmT) [Streptococcus pneumoniae R6]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAGTACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTAAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTTATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.531

99.821

0.724
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667

Multiple sequence alignment