Detailed information NTG0021502

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SP_RS13735
• Genome accession: NC_003028
• Coordinates: 510850..511437 (-)
• Length: 195 a.a.
• NCBI ID: WP_000205166.1
• Uniprot ID: Q9ETN5
• Organism: Streptococcus pneumoniae TIGR4
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 505850..516437

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP_RS02580 (SP_0527)	-	506312..507652 (+)	1341	WP_001017646.1	sensor histidine kinase	-
SP_RS02585 (SP_0528)	blpC	507723..507851 (-)	129	WP_000358815.1	quorum-sensing system pheromone BlpC	-
SP_RS02590 (SP_0529)	-	507908..509269 (-)	1362	WP_001069075.1	bacteriocin secretion accessory protein	-
SP_RS13725	comA/nlmT	509280..509927 (-)	648	WP_078064020.1	ATP-binding cassette domain-containing protein	Regulator
SP_RS13730	comA/nlmT	509943..510956 (-)	1014	WP_307772067.1	ABC transporter transmembrane domain-containing protein	Regulator
SP_RS13735	comA/nlmT	510850..511437 (-)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
SP_RS02610 (SP_0531)	blpI	511719..511916 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
SP_RS02615 (SP_0532)	blpJ	512383..512652 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
SP_RS02620 (SP_0533)	blpU	512721..512951 (+)	231	WP_000379967.1	bacteriocin-like peptide BlpU	-
SP_RS02625	-	512954..513073 (+)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
SP_RS13000 (SP_0535)	-	513370..513534 (+)	165	WP_000727118.1	hypothetical protein	-
SP_RS02640 (SP_0536)	-	513531..513935 (+)	405	WP_000846943.1	hypothetical protein	-
SP_RS11830	-	514138..514942 (+)	805	WP_100214365.1	IS5 family transposase	-
SP_RS02655 (SP_0539)	blpM	515092..515346 (+)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-
SP_RS02660 (SP_0540)	blpN	515362..515565 (+)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
SP_RS02665 (SP_0541)	cipB	515809..515958 (+)	150	WP_001818346.1	bacteriocin-like peptide BlpO	Regulator
SP_RS02670	-	516062..516181 (+)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22270.71 Da
• Isoelectric Point: 9.6188

>NTDB_id=21502 SP_RS13735 WP_000205166.1 510850..511437(-) (comA/nlmT) [Streptococcus pneumoniae TIGR4]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=21502 SP_RS13735 WP_000205166.1 510850..511437(-) (comA/nlmT) [Streptococcus pneumoniae TIGR4]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

3D structure

• AlphaFold DB: Q9ETN5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	59.89	93.333	0.559
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497