Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   BVD85_RS10365 Genome accession   NZ_CP018908
Coordinates   2069054..2070250 (+) Length   398 a.a.
NCBI ID   WP_012028059.1    Uniprot ID   D5AF49
Organism   Streptococcus suis strain SS2-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2064054..2075250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BVD85_RS10335 (BVD85_10335) - 2064713..2067292 (+) 2580 WP_012028056.1 YfhO family protein -
  BVD85_RS10355 (BVD85_10355) - 2067693..2068376 (-) 684 WP_012775416.1 YoaK family protein -
  BVD85_RS10360 (BVD85_10360) rlmH 2068401..2068880 (-) 480 WP_075340283.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  BVD85_RS10365 (BVD85_10365) htrA 2069054..2070250 (+) 1197 WP_012028059.1 S1C family serine protease Regulator
  BVD85_RS10370 (BVD85_10370) spo0J 2070311..2071075 (+) 765 WP_012775418.1 ParB/RepB/Spo0J family partition protein Regulator
  BVD85_RS10375 (BVD85_10375) dnaA 2071278..2072651 (+) 1374 WP_011921628.1 chromosomal replication initiator protein DnaA -
  BVD85_RS10380 (BVD85_10380) dnaN 2072805..2073941 (+) 1137 WP_004194538.1 DNA polymerase III subunit beta -
  BVD85_RS10385 (BVD85_10385) - 2074033..2074914 (+) 882 WP_011921629.1 diacylglycerol/lipid kinase family protein -
  BVD85_RS10390 (BVD85_10390) - 2074924..2075127 (+) 204 WP_011922523.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 41866.92 Da        Isoelectric Point: 4.6543

>NTDB_id=211737 BVD85_RS10365 WP_012028059.1 2069054..2070250(+) (htrA) [Streptococcus suis strain SS2-1]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGVIFGNIESSDELAVAGEGSGVIYKKYGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=211737 BVD85_RS10365 WP_012028059.1 2069054..2070250(+) (htrA) [Streptococcus suis strain SS2-1]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTGTCAGCCTCTTTCTTCCAGCCACAGGTGCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAATCAGCC
AACAATAGTCTTGGTGTTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAATATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCCGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(103-248)

PDZ domain (PDZ_2)

(293-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D5AF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

59.194

99.749

0.59
  htrA Streptococcus gordonii str. Challis substr. CH1

58.987

99.246

0.585
  htrA Streptococcus pneumoniae D39

57.252

98.744

0.565
  htrA Streptococcus pneumoniae TIGR4

57.252

98.744

0.565
  htrA Streptococcus mitis NCTC 12261

57.252

98.744

0.565
  htrA Streptococcus pneumoniae R6

57.252

98.744

0.565
  htrA Streptococcus pneumoniae Rx1

57.252

98.744

0.565

Multiple sequence alignment