Detailed information NTG0211246

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: BUW91_RS25950
• Genome accession: NZ_CP018874
• Coordinates: 5036849..5037910 (-)
• Length: 353 a.a.
• NCBI ID: WP_301337466.1
• Uniprot ID: -
• Organism: Priestia megaterium strain JX285
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 5031849..5042910

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUW91_RS25930 (BUW91_25950)	-	5032571..5034469 (+)	1899	WP_029319481.1	alkaline phosphatase PhoX	-
BUW91_RS25935 (BUW91_25955)	-	5034886..5035884 (+)	999	WP_029319482.1	tRNA-dihydrouridine synthase	-
BUW91_RS25940 (BUW91_25960)	rlmH	5036054..5036533 (-)	480	WP_013085547.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
BUW91_RS25945 (BUW91_25965)	-	5036617..5036775 (-)	159	WP_013059901.1	CxxH/CxxC protein	-
BUW91_RS25950 (BUW91_25970)	htrA	5036849..5037910 (-)	1062	WP_301337466.1	trypsin-like peptidase domain-containing protein	Regulator
BUW91_RS25955 (BUW91_25975)	-	5038138..5038932 (-)	795	WP_014457688.1	MBL fold metallo-hydrolase	-
BUW91_RS25960 (BUW91_25980)	yycI	5038951..5039730 (-)	780	WP_029319486.1	two-component system regulatory protein YycI	-
BUW91_RS25965 (BUW91_25985)	yycH	5039717..5041078 (-)	1362	WP_225049784.1	two-component system activity regulator YycH	-

Sequence

Protein

• Length: 353 a.a.
• Molecular weight: 37884.83 Da
• Isoelectric Point: 5.1327

>NTDB_id=211246 BUW91_RS25950 WP_301337466.1 5036849..5037910(-) (htrA) [Priestia megaterium strain JX285]
MPDGWMTDENRDEQTGSTIQKSVSLDVTTAVTKAVSEANAAVVGVVNIQNSESFWNDERTDAGTGSGVIYKKQGNKAYIV
TNYHVIKGANEIEVSFSNGTRVSAKILGSDDLMDLAVLEIDAGHVTKVATFGNSDKLKAGEPVIAIGNPLGLQFSGSVTQ
GVVSGVNRVIPQDLNGDGNPDWQSEVIQTDAAINPGNSGGALVNIDGELIGINSMKIAQEAVEGIGLAIPINMARPIIND
LERYGEVRRPYLGVSTLSLSEVSGYHLKETLKLPHDVVNGVAVLKVEPGSPAAKAGLKEYDVIVELDHSKVRDIATLRKH
LYIEKEIGDKMNVTFYRDGKKKSTEVKLTRQMK

Nucleotide

• Length: 1062 bp

>NTDB_id=211246 BUW91_RS25950 WP_301337466.1 5036849..5037910(-) (htrA) [Priestia megaterium strain JX285]
TTGCCAGATGGATGGATGACGGATGAAAATAGAGATGAACAAACGGGATCTACCATCCAAAAATCAGTATCTCTTGATGT
CACTACGGCCGTCACAAAAGCTGTTTCTGAAGCCAATGCAGCAGTTGTAGGAGTTGTAAACATTCAGAACTCTGAAAGCT
TTTGGAATGATGAACGAACTGATGCCGGAACGGGCTCAGGTGTTATTTACAAAAAGCAAGGCAACAAAGCTTATATTGTG
ACAAACTATCATGTCATTAAAGGCGCTAACGAAATTGAAGTGAGCTTCAGTAACGGTACAAGGGTATCGGCTAAAATTCT
TGGCAGCGATGATTTAATGGACTTAGCAGTTCTTGAAATTGACGCAGGCCACGTGACAAAAGTGGCTACCTTCGGAAATT
CTGATAAGCTTAAAGCTGGTGAACCAGTGATTGCTATCGGAAACCCGTTAGGCCTTCAATTTTCTGGCTCCGTTACACAA
GGAGTTGTCTCAGGGGTTAACCGTGTCATTCCTCAAGATTTGAATGGCGATGGAAACCCTGATTGGCAATCAGAAGTTAT
TCAAACAGATGCCGCCATTAACCCTGGTAATAGCGGGGGTGCTCTTGTTAATATTGATGGTGAATTAATCGGTATTAATT
CCATGAAAATTGCCCAAGAAGCAGTAGAAGGCATTGGTCTTGCCATTCCAATCAACATGGCTAGGCCCATTATTAATGAC
TTAGAACGATATGGTGAAGTCAGACGTCCGTATCTTGGAGTTAGTACACTATCATTAAGTGAGGTATCAGGGTATCATTT
AAAAGAAACCCTTAAGTTACCGCATGATGTAGTAAACGGAGTTGCTGTTCTAAAAGTCGAGCCAGGTTCGCCAGCCGCTA
AAGCCGGATTAAAGGAATATGATGTGATTGTTGAGTTAGATCACAGCAAAGTAAGGGACATTGCGACACTTCGCAAACAC
CTCTACATTGAAAAAGAAATTGGCGATAAAATGAACGTAACGTTCTATCGCGATGGCAAAAAGAAATCCACAGAAGTAAA
ATTAACGCGTCAAATGAAGTGA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (262-349)

• PDZ domain (PDZ_2) (250-348)

• Trypsin-like peptidase domain (Trypsin_2) (65-212)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	46.866	100	0.487
htrA	Streptococcus pneumoniae Rx1	44.277	94.051	0.416
htrA	Streptococcus pneumoniae D39	44.277	94.051	0.416
htrA	Streptococcus pneumoniae R6	44.277	94.051	0.416
htrA	Streptococcus pneumoniae TIGR4	44.277	94.051	0.416
htrA	Streptococcus mitis NCTC 12261	43.675	94.051	0.411
htrA	Streptococcus gordonii str. Challis substr. CH1	40.96	100	0.411