Detailed information NTG0210138

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: BTZ13_RS06890
• Genome accession: NZ_CP018776
• Coordinates: 1467723..1468049 (+)
• Length: 108 a.a.
• NCBI ID: WP_047130996.1
• Uniprot ID: A0A143P863
• Organism: Staphylococcus condimenti strain StO 2014-01
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1462723..1473049

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BTZ13_RS06860 (BTZ13_06860)	-	1463476..1463676 (+)	201	WP_047130990.1	YqgQ family protein	-
BTZ13_RS06865 (BTZ13_06865)	-	1463676..1464662 (+)	987	WP_047130991.1	ROK family glucokinase	-
BTZ13_RS06870 (BTZ13_06870)	-	1464662..1464991 (+)	330	WP_047130992.1	MTH1187 family thiamine-binding protein	-
BTZ13_RS06875 (BTZ13_06875)	-	1464991..1465614 (+)	624	WP_047130993.1	MBL fold metallo-hydrolase	-
BTZ13_RS06880 (BTZ13_06880)	comGA	1465686..1466660 (+)	975	WP_047130994.1	competence type IV pilus ATPase ComGA	Machinery gene
BTZ13_RS06885 (BTZ13_06885)	comGB	1466632..1467705 (+)	1074	WP_047130995.1	competence type IV pilus assembly protein ComGB	-
BTZ13_RS06890 (BTZ13_06890)	comGC	1467723..1468049 (+)	327	WP_047130996.1	competence type IV pilus major pilin ComGC	Machinery gene
BTZ13_RS06895 (BTZ13_06895)	-	1468069..1468482 (+)	414	WP_232011920.1	prepilin-type cleavage/methylation domain-containing protein	-
BTZ13_RS13230 (BTZ13_06900)	-	1468463..1468756 (+)	294	WP_047130998.1	hypothetical protein	-
BTZ13_RS06905 (BTZ13_06905)	comGF	1468698..1469174 (+)	477	WP_047130999.1	competence type IV pilus minor pilin ComGF	-
BTZ13_RS06915 (BTZ13_06915)	-	1469339..1469878 (+)	540	WP_152650907.1	shikimate kinase	-
BTZ13_RS06920 (BTZ13_06920)	gcvT	1470070..1471164 (+)	1095	WP_070704818.1	glycine cleavage system aminomethyltransferase GcvT	-
BTZ13_RS06925 (BTZ13_06925)	gcvPA	1471185..1472531 (+)	1347	WP_047131001.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12114.29 Da
• Isoelectric Point: 9.7598

>NTDB_id=210138 BTZ13_RS06890 WP_047130996.1 1467723..1468049(+) (comGC) [Staphylococcus condimenti strain StO 2014-01]
MKKYYLLFKNKNLKAFTLLEMLLVLLVISVLLILIIPNIAKQSEHVQSTGCEAQQKMVNSQIEAFTLKNNQKPNSIDELV
TQGYLKEGQKKCKSGESITIKNGEASIS

Nucleotide

• Length: 327 bp

>NTDB_id=210138 BTZ13_RS06890 WP_047130996.1 1467723..1468049(+) (comGC) [Staphylococcus condimenti strain StO 2014-01]
ATGAAAAAATATTACTTATTATTTAAAAATAAAAACTTAAAAGCTTTTACATTGTTAGAAATGTTGCTCGTATTGTTGGT
TATCAGTGTATTATTAATTTTGATTATACCTAACATTGCTAAGCAATCTGAACATGTTCAATCTACAGGTTGTGAGGCAC
AGCAAAAAATGGTGAATAGTCAAATAGAAGCCTTTACACTTAAAAATAACCAAAAGCCCAATTCTATCGATGAACTTGTA
ACACAAGGTTATCTAAAGGAAGGGCAAAAGAAATGTAAATCTGGAGAAAGTATAACAATTAAAAATGGTGAAGCTTCAAT
TAGCTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-35)

3D structure

• AlphaFold DB: A0A143P863

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	70.526	87.963	0.62
comGC	Staphylococcus aureus N315	70.526	87.963	0.62
comGC/cglC	Streptococcus mitis SK321	43.396	98.148	0.426
comGC/cglC	Streptococcus pneumoniae R6	42.453	98.148	0.417
comGC/cglC	Streptococcus pneumoniae D39	42.453	98.148	0.417
comGC/cglC	Streptococcus pneumoniae TIGR4	42.453	98.148	0.417
comGC/cglC	Streptococcus pneumoniae Rx1	42.453	98.148	0.417
comGC/cglC	Streptococcus mitis NCTC 12261	45.652	85.185	0.389
comGC	Bacillus subtilis subsp. subtilis str. 168	41.667	88.889	0.37