Detailed information NTG0020879

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SPY_RS04880
• Genome accession: NC_002737
• Coordinates: 955776..956612 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes M1 GAS
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 950776..961612

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPY_RS04850 (SPy1157)	-	951330..951698 (+)	369	WP_010922310.1	hypothetical protein	-
SPY_RS04855 (SPy1158)	-	951748..952659 (-)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
SPY_RS04860 (SPy1159)	-	952776..953426 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
SPY_RS04865 (SPy1160)	-	953423..953863 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
SPY_RS04870 (SPy1161)	ylqF	954082..954930 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
SPY_RS04875 (SPy1162)	-	954920..955711 (+)	792	WP_010922313.1	ribonuclease HII	-
SPY_RS04880 (SPy1163)	dprA	955776..956612 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
SPY_RS04885 (SPy1164)	topA	956719..958848 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
SPY_RS04890 (SPy1168)	-	958923..959805 (-)	883	Protein_930	LysR family transcriptional regulator	-
SPY_RS04895 (SPy1169)	-	959818..960363 (+)	546	Protein_931	PTS sugar transporter subunit IIC	-
SPY_RS04900 (SPy1170)	-	960378..961370 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=20879 SPY_RS04880 WP_010922314.1 955776..956612(+) (dprA) [Streptococcus pyogenes M1 GAS]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=20879 SPY_RS04880 WP_010922314.1 955776..956612(+) (dprA) [Streptococcus pyogenes M1 GAS]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367