Detailed information NTG0206863

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: BSR19_RS08090
• Genome accession: NZ_CP018187
• Coordinates: 1787443..1789683 (-)
• Length: 746 a.a.
• NCBI ID: WP_156246978.1
• Uniprot ID: A0AB37DBN5
• Organism: Streptococcus salivarius strain ICDC2
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1782443..1794683

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR19_RS08070 (BSR19_08180)	-	1783307..1784167 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
BSR19_RS08075 (BSR19_08185)	spxR	1784211..1785491 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
BSR19_RS08080 (BSR19_08190)	-	1785484..1786029 (-)	546	WP_049545582.1	GNAT family N-acetyltransferase	-
BSR19_RS08085 (BSR19_08195)	-	1786095..1787357 (-)	1263	WP_002884638.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
BSR19_RS08090 (BSR19_08200)	comEC/celB	1787443..1789683 (-)	2241	WP_156246978.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BSR19_RS08095 (BSR19_08205)	comEA	1789673..1790368 (-)	696	WP_049545585.1	helix-hairpin-helix domain-containing protein	Machinery gene
BSR19_RS08100 (BSR19_08210)	-	1790477..1791232 (-)	756	WP_049545586.1	lysophospholipid acyltransferase family protein	-
BSR19_RS08105 (BSR19_08215)	-	1791362..1792297 (+)	936	WP_049545587.1	polysaccharide deacetylase family protein	-
BSR19_RS08110 (BSR19_08220)	-	1792347..1793111 (+)	765	WP_049545588.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
BSR19_RS08115 (BSR19_08225)	-	1793115..1793384 (+)	270	WP_008535312.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84404.19 Da
• Isoelectric Point: 9.7179

>NTDB_id=206863 BSR19_RS08090 WP_156246978.1 1787443..1789683(-) (comEC/celB) [Streptococcus salivarius strain ICDC2]
MWLKKAPISLFSLSLLIAALYFTIFITNVYAIGTFVFLMVCFLKHHCKNKTALKLVGLVGSFFLVYFLFLHHRASIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKITLTTATGQRNFQGFNYQSY
LASQGIYRIAQIERLDQVVPQKSLSPLAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLQKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKCPVRTLKAGDNLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPNLKASILKAGHHGSKGSSSEAFLDQLQPTLALVSAGENNRYKHPNDETLKRFKERH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=206863 BSR19_RS08090 WP_156246978.1 1787443..1789683(-) (comEC/celB) [Streptococcus salivarius strain ICDC2]
ATGTGGCTTAAAAAAGCGCCAATCAGTCTTTTTTCCTTGTCTCTTTTAATAGCTGCCCTTTATTTTACGATTTTTATCAC
TAATGTTTATGCTATTGGGACTTTTGTCTTTCTGATGGTCTGTTTTTTGAAGCATCATTGTAAGAATAAGACAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCATCATAGAGCTAGCATACAAGATAAACAA
GCCCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCCGCTATCGGTAA
GGCAAAGGGACAAACCTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTCAAGACTACTAGTCAAA
CGCTAGTATTAAAAGGGAAAATTACGTTAACCACAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAATCTTAT
CTAGCCAGTCAAGGTATTTATCGAATCGCTCAGATTGAGCGCTTGGACCAAGTGGTACCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAATTGAGGAGGAGGGCTTTAGTTCATATCCAGACGCACTTTCCTAATCCTATGAGACACTATATGA
CAGGCTTGCTCTTTGGGTATTTGGATAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGATTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTGCCTTTTTCCTTATGCTATGGTTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTAGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGGATAACCTTGCTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGAAGA
GATGTCATCTCTTCAAAAGTCAATCTGTACGAGCTTGGTATTGAGTCTTGGGATTTTGCCTTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGCTTTCTCTTGCCTGTCTTGACG
GTCTTCTTTGCCCTTTCAGGACTAGTAATCTTTTCTCAAATTAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGGTCAAAGGAAAAATGGCAAGAGGCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTACCTACAGGCTAGAGGAGTGTCTCAAATTGACCATCTGGTTCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAATGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGCAGTTTTCTGTTTACTGGTGATTTGGAAAAAGAAGGTGAGGAGGAACTGATGGCCAGTTATCCCAATTTAAA
GGCAAGTATCCTCAAGGCTGGACACCACGGTTCAAAGGGTTCTTCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCACCC
TTGCCCTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACTTTGAAGCGTTTTAAGGAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAAGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-700)

• Domain of unknown function (DUF4131) (DUF4131) (30-171)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.797	100	0.489
comEC/celB	Streptococcus mitis SK321	48.465	100	0.487
comEC/celB	Streptococcus pneumoniae R6	47.397	100	0.476
comEC/celB	Streptococcus pneumoniae D39	47.397	100	0.476
comEC/celB	Streptococcus pneumoniae Rx1	47.397	100	0.476
comEC/celB	Streptococcus pneumoniae TIGR4	47.263	100	0.475
comEC	Lactococcus lactis subsp. cremoris KW2	43.089	98.928	0.426