Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   BSR19_RS01510 Genome accession   NZ_CP018187
Coordinates   279734..281830 (+) Length   698 a.a.
NCBI ID   WP_002889921.1    Uniprot ID   J7TGZ7
Organism   Streptococcus salivarius strain ICDC2     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 274734..286830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS01485 (BSR19_01485) trkA 274825..276174 (-) 1350 WP_060973157.1 Trk system potassium transporter TrkA -
  BSR19_RS01490 (BSR19_01490) - 276452..276961 (+) 510 WP_021143543.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  BSR19_RS01495 (BSR19_01495) - 277272..277829 (+) 558 WP_049545714.1 ECF transporter S component -
  BSR19_RS01500 (BSR19_01500) - 277832..278482 (+) 651 WP_049545715.1 phosphatase PAP2 family protein -
  BSR19_RS01505 (BSR19_01505) comR 278660..279559 (+) 900 WP_049545716.1 helix-turn-helix transcriptional regulator Regulator
  BSR19_RS01510 (BSR19_01510) comA 279734..281830 (+) 2097 WP_002889921.1 peptide cleavage/export ABC transporter Regulator
  BSR19_RS01515 (BSR19_01515) - 281941..282273 (+) 333 WP_002886546.1 DUF805 domain-containing protein -
  BSR19_RS01520 (BSR19_01520) - 282324..283715 (-) 1392 WP_156246365.1 DUF4153 domain-containing protein -
  BSR19_RS01525 (BSR19_01525) - 284122..284637 (+) 516 WP_002886548.1 AmiS/UreI family transporter -
  BSR19_RS01530 (BSR19_01530) - 284662..284964 (+) 303 WP_002889924.1 urease subunit gamma -
  BSR19_RS01535 (BSR19_01535) - 284976..285287 (+) 312 WP_002886559.1 urease subunit beta -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78438.41 Da        Isoelectric Point: 9.2880

>NTDB_id=206831 BSR19_RS01510 WP_002889921.1 279734..281830(+) (comA) [Streptococcus salivarius strain ICDC2]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIVHVVKEGGLQHYYTVFGQIKGQLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGEAYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQAIIDRLIPQGANNLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALIVQNQSLFVMTLTVVPFYVLII
VAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYREIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAF
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNLFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=206831 BSR19_RS01510 WP_002889921.1 279734..281830(+) (comA) [Streptococcus salivarius strain ICDC2]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGAGAGTTGGCTCAGACTTCTCGTGAAGGTACCTCTGCGCTTGGTTTGGTGG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGTACATGTGGTTAAAGAAGGTGGGCTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGCAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAATTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAGCCTATACTAAATACAAAGAAGATGTACCTGGACTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTATTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAAGCTATTATCGACCGCTTGATTCCTCAGGGGGCCAATAATCTTCTGACTATGATTTCGCTAGGCTTATGTATCTCTT
ATCTTGCTCAACAAGTTTTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGTAATTACCTGTCCATTGCTGTCATT
CTTCCTTATATCAAGCATGTCCTTTCCTTGCCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACGTCACGTTT
TGGGGATGCTAACACTATTATAGATGCTCTAGCTTCAACTATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTGTACAAAATCAGTCACTTTTTGTGATGACTCTCACAGTAGTTCCTTTTTATGTATTAATCATT
GTGGCATTCTATAAGCTTTTTGAGAAAGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGGGTTGAGGAAAGACGTTATCGGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCCTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGGTTAAAGACAGGGGTTCAGTTAGTTTCT
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTCATGGAAGGGCAACTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATTAATCTCCAATCCAAAATTCAGCAAGCCAAAGTCGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTTTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACTCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGAAAAACGACCTTAGCTAAAATGTTGTCAGGTTATTATACGAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCCATTAGCCATGCGGAGTTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACGGGGACGATTTTAGAGAATCTGCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGCTTTCAGACCCAAGTATCTGAAGACGGTGGTCTATCAG
GTGGTCAAAAACAACGCTTGGCTATAGCGAGGGCTCTCTTGTCCAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTTGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTACGTCAACATGTCAGTCGTGTAGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTCCTAATTTCAATC
TATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(167-436)

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter (ABC_tran)

(494-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TGZ7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.067

100

0.533
  comA Streptococcus mitis NCTC 12261

52.639

100

0.529
  comA Streptococcus gordonii str. Challis substr. CH1

53.017

99.713

0.529
  comA Streptococcus pneumoniae D39

52.496

100

0.527
  comA Streptococcus pneumoniae R6

52.496

100

0.527
  comA Streptococcus pneumoniae Rx1

52.496

100

0.527
  comA Streptococcus pneumoniae TIGR4

52.354

100

0.526
  comA/nlmT Streptococcus mutans UA159

50.58

98.854

0.5

Multiple sequence alignment