Detailed information NTG0206091

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: BMJ42_RS11035
• Genome accession: NZ_CP018136
• Coordinates: 1982986..1983447 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SP49
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1977986..1988447

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BMJ42_RS11000 (BMJ42_02086)	-	1978290..1979114 (-)	825	WP_001832473.1	membrane protein insertase YidC	-
BMJ42_RS11005 (BMJ42_02087)	rnpA	1979089..1979460 (-)	372	WP_000739244.1	ribonuclease P protein component	-
BMJ42_RS13655	-	1979477..1979608 (-)	132	WP_000768904.1	hypothetical protein	-
BMJ42_RS11010 (BMJ42_02088)	-	1979609..1980799 (-)	1191	WP_000167752.1	acetate kinase	-
BMJ42_RS11015 (BMJ42_02089)	comYH	1980850..1981803 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
BMJ42_RS12455	-	1981864..1982458 (-)	595	Protein_2032	class I SAM-dependent methyltransferase	-
BMJ42_RS11030 (BMJ42_02092)	comGG/cglG	1982595..1983008 (-)	414	WP_000265620.1	competence type IV pilus minor pilin ComGG	Machinery gene
BMJ42_RS11035 (BMJ42_02093)	comGF/cglF	1982986..1983447 (-)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
BMJ42_RS11040 (BMJ42_02094)	comGE/cglE	1983410..1983712 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
BMJ42_RS11045 (BMJ42_02095)	comGD/cglD	1983675..1984079 (-)	405	WP_000588023.1	competence type IV pilus minor pilin ComGD	Machinery gene
BMJ42_RS11050 (BMJ42_02096)	comGC/cglC	1984072..1984398 (-)	327	WP_000738630.1	comG operon protein ComGC	Machinery gene
BMJ42_RS11055 (BMJ42_02097)	comGB/cglB	1984400..1985416 (-)	1017	WP_073177425.1	competence type IV pilus assembly protein ComGB	Machinery gene
BMJ42_RS11060 (BMJ42_02098)	comGA/cglA/cilD	1985364..1986305 (-)	942	WP_000249559.1	competence type IV pilus ATPase ComGA	Machinery gene
BMJ42_RS11065 (BMJ42_02099)	-	1986381..1986746 (-)	366	WP_000286415.1	DUF1033 family protein	-
BMJ42_RS11070 (BMJ42_02100)	-	1987013..1988268 (+)	1256	WP_370657740.1	ISL3 family transposase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17850.40 Da
• Isoelectric Point: 8.0016

>NTDB_id=206091 BMJ42_RS11035 WP_000250540.1 1982986..1983447(-) (comGF/cglF) [Streptococcus pneumoniae strain SP49]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=206091 BMJ42_RS11035 WP_000250540.1 1982986..1983447(-) (comGF/cglF) [Streptococcus pneumoniae strain SP49]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	93.464	100	0.935
comGF/cglF	Streptococcus mitis NCTC 12261	92.157	100	0.922