Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   BMJ42_RS11015 Genome accession   NZ_CP018136
Coordinates   1980850..1981803 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain SP49     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1975850..1986803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BMJ42_RS10990 (BMJ42_02084) - 1976611..1977234 (-) 624 WP_000932657.1 hypothetical protein -
  BMJ42_RS10995 (BMJ42_02085) jag 1977285..1978271 (-) 987 WP_000260027.1 RNA-binding cell elongation regulator Jag/EloR -
  BMJ42_RS11000 (BMJ42_02086) - 1978290..1979114 (-) 825 WP_001832473.1 membrane protein insertase YidC -
  BMJ42_RS11005 (BMJ42_02087) rnpA 1979089..1979460 (-) 372 WP_000739244.1 ribonuclease P protein component -
  BMJ42_RS13655 - 1979477..1979608 (-) 132 WP_000768904.1 hypothetical protein -
  BMJ42_RS11010 (BMJ42_02088) - 1979609..1980799 (-) 1191 WP_000167752.1 acetate kinase -
  BMJ42_RS11015 (BMJ42_02089) comYH 1980850..1981803 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  BMJ42_RS12455 - 1981864..1982458 (-) 595 Protein_2032 class I SAM-dependent methyltransferase -
  BMJ42_RS11030 (BMJ42_02092) comGG/cglG 1982595..1983008 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  BMJ42_RS11035 (BMJ42_02093) comGF/cglF 1982986..1983447 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  BMJ42_RS11040 (BMJ42_02094) comGE/cglE 1983410..1983712 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  BMJ42_RS11045 (BMJ42_02095) comGD/cglD 1983675..1984079 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  BMJ42_RS11050 (BMJ42_02096) comGC/cglC 1984072..1984398 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  BMJ42_RS11055 (BMJ42_02097) comGB/cglB 1984400..1985416 (-) 1017 WP_073177425.1 competence type IV pilus assembly protein ComGB Machinery gene
  BMJ42_RS11060 (BMJ42_02098) comGA/cglA/cilD 1985364..1986305 (-) 942 WP_000249559.1 competence type IV pilus ATPase ComGA Machinery gene
  BMJ42_RS11065 (BMJ42_02099) - 1986381..1986746 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=206089 BMJ42_RS11015 WP_000345126.1 1980850..1981803(-) (comYH) [Streptococcus pneumoniae strain SP49]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=206089 BMJ42_RS11015 WP_000345126.1 1980850..1981803(-) (comYH) [Streptococcus pneumoniae strain SP49]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAACCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment