Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   BMJ42_RS11040 Genome accession   NZ_CP018136
Coordinates   1983410..1983712 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SP49     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1978410..1988712
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BMJ42_RS11005 (BMJ42_02087) rnpA 1979089..1979460 (-) 372 WP_000739244.1 ribonuclease P protein component -
  BMJ42_RS13655 - 1979477..1979608 (-) 132 WP_000768904.1 hypothetical protein -
  BMJ42_RS11010 (BMJ42_02088) - 1979609..1980799 (-) 1191 WP_000167752.1 acetate kinase -
  BMJ42_RS11015 (BMJ42_02089) comYH 1980850..1981803 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  BMJ42_RS12455 - 1981864..1982458 (-) 595 Protein_2032 class I SAM-dependent methyltransferase -
  BMJ42_RS11030 (BMJ42_02092) comGG/cglG 1982595..1983008 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  BMJ42_RS11035 (BMJ42_02093) comGF/cglF 1982986..1983447 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  BMJ42_RS11040 (BMJ42_02094) comGE/cglE 1983410..1983712 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  BMJ42_RS11045 (BMJ42_02095) comGD/cglD 1983675..1984079 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  BMJ42_RS11050 (BMJ42_02096) comGC/cglC 1984072..1984398 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  BMJ42_RS11055 (BMJ42_02097) comGB/cglB 1984400..1985416 (-) 1017 WP_073177425.1 competence type IV pilus assembly protein ComGB Machinery gene
  BMJ42_RS11060 (BMJ42_02098) comGA/cglA/cilD 1985364..1986305 (-) 942 WP_000249559.1 competence type IV pilus ATPase ComGA Machinery gene
  BMJ42_RS11065 (BMJ42_02099) - 1986381..1986746 (-) 366 WP_000286415.1 DUF1033 family protein -
  BMJ42_RS11070 (BMJ42_02100) - 1987013..1988268 (+) 1256 WP_370657740.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=206092 BMJ42_RS11040 WP_000413382.1 1983410..1983712(-) (comGE/cglE) [Streptococcus pneumoniae strain SP49]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=206092 BMJ42_RS11040 WP_000413382.1 1983410..1983712(-) (comGE/cglE) [Streptococcus pneumoniae strain SP49]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment