Detailed information NTG0205210

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: A2U21_RS08485
• Genome accession: NZ_CP018034
• Coordinates: 1647840..1649102 (-)
• Length: 420 a.a.
• NCBI ID: WP_005712502.1
• Uniprot ID: -
• Organism: Glaesserella parasuis str. Nagasaki
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1642840..1654102

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2U21_RS08450 (A2U21_08160)	-	1642853..1643272 (+)	420	WP_005714137.1	hotdog fold thioesterase	-
A2U21_RS12980	-	1643823..1644359 (-)	537	WP_418251396.1	IS256 family transposase, variant Zn-binding type	-
A2U21_RS08460 (A2U21_08170)	trxA	1644656..1644970 (-)	315	WP_005712493.1	thioredoxin	-
A2U21_RS08465 (A2U21_08175)	-	1645267..1645896 (-)	630	WP_010785950.1	LysE family transporter	-
A2U21_RS08470 (A2U21_08180)	-	1645898..1646368 (-)	471	WP_005712497.1	phosphatidylglycerophosphatase A	-
A2U21_RS08475 (A2U21_08185)	thiL	1646371..1647339 (-)	969	WP_021110497.1	thiamine-phosphate kinase	-
A2U21_RS08480 (A2U21_08190)	nusB	1647348..1647761 (-)	414	WP_010785952.1	transcription antitermination factor NusB	-
A2U21_RS08485 (A2U21_08195)	comE	1647840..1649102 (-)	1263	WP_005712502.1	type IV pilus secretin PilQ	Machinery gene
A2U21_RS08490 (A2U21_08200)	comD	1649112..1649453 (-)	342	WP_230205898.1	hypothetical protein	Machinery gene
A2U21_RS08495 (A2U21_08205)	comC	1649498..1650028 (-)	531	WP_015940159.1	hypothetical protein	Machinery gene
A2U21_RS08500 (A2U21_08210)	comB	1650025..1650546 (-)	522	WP_005712507.1	hypothetical protein	Machinery gene
A2U21_RS08505 (A2U21_08215)	comA	1650522..1651199 (-)	678	WP_005712510.1	hypothetical protein	Machinery gene
A2U21_RS08510 (A2U21_08220)	-	1651353..1653908 (+)	2556	WP_035498541.1	penicillin-binding protein 1A	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 47051.05 Da
• Isoelectric Point: 8.9182

>NTDB_id=205210 A2U21_RS08485 WP_005712502.1 1647840..1649102(-) (comE) [Glaesserella parasuis str. Nagasaki]
MRYLFLLFFATFPVLANQQISLSIKNAPTAEIIGYLAEETGKNITISDEIKDTKNFRVEKSHFDEILNSLIKTHQLNLKK
ENGIYYIHQAQEHKQHTTAQLVNALPKLITKTIKLHYSKASEVIESLTKGQGNLLSENGYLHFDDRSNSIIVKDSAASVK
NFTQLIETLDKPTEQIAIEARIVTISSEHLQQLGVRWGLFSPNENHYKLAGNLEGNGLTTNNLNVNFPVNPSASVALQIA
AINSRVLHLELTALESENNIEIIASPRLLTTDKKPASIKQGTEIPYAMYSKKKEITDIEFREAVLGLEVTPHISKQNQIL
LDLAISQNSPNNQMNNMMATIDKQEINTQVLAKHGETIVLGGIFQHLIAKGEDKVPLLGSIPVIKRLFSQNRDKISKREL
VIFVTPYIVKSEKMGAEKQK

Nucleotide

• Length: 1263 bp

>NTDB_id=205210 A2U21_RS08485 WP_005712502.1 1647840..1649102(-) (comE) [Glaesserella parasuis str. Nagasaki]
ATGCGTTATTTATTCCTGCTATTCTTTGCTACTTTTCCTGTATTAGCAAACCAACAAATTTCGCTTTCTATAAAAAATGC
CCCTACGGCAGAAATTATTGGTTATTTAGCTGAAGAAACGGGAAAAAATATTACGATTTCAGATGAGATTAAAGATACAA
AAAATTTCAGAGTAGAAAAAAGCCATTTTGATGAGATATTAAATAGTTTAATCAAAACACATCAATTAAATTTAAAAAAA
GAAAATGGCATTTACTATATTCATCAAGCCCAAGAACATAAACAACATACTACGGCACAATTAGTTAATGCTCTGCCTAA
ATTAATCACCAAAACAATCAAGTTACACTATTCCAAAGCCTCTGAAGTAATAGAGTCTTTGACAAAAGGGCAAGGCAACT
TGCTATCAGAGAATGGTTATCTTCATTTTGATGATCGCAGTAATAGTATTATCGTCAAAGACAGTGCCGCATCGGTTAAA
AACTTTACTCAACTTATTGAAACCCTAGATAAACCAACGGAACAAATTGCAATTGAAGCCCGAATTGTCACGATCAGCAG
TGAACATTTACAACAACTTGGCGTGCGTTGGGGCTTATTTTCCCCTAACGAAAATCACTACAAATTGGCAGGAAACTTAG
AGGGCAACGGATTAACTACCAACAACTTAAACGTAAATTTTCCAGTAAATCCGTCCGCTTCCGTTGCCTTACAAATTGCC
GCTATCAACAGCCGTGTACTTCATTTAGAACTCACCGCATTAGAGAGCGAAAATAACATTGAGATCATTGCAAGCCCTCG
CTTACTCACAACAGATAAAAAACCAGCGAGTATCAAACAAGGTACAGAGATTCCTTATGCAATGTACAGTAAGAAAAAGG
AAATCACCGATATTGAATTTCGTGAAGCGGTTTTGGGGCTAGAAGTCACGCCACATATTTCTAAACAAAATCAGATTTTG
TTAGATCTTGCCATTAGCCAAAATTCGCCAAATAACCAGATGAACAATATGATGGCAACGATTGATAAACAAGAAATTAA
TACACAAGTCCTTGCTAAACACGGCGAAACCATCGTATTAGGCGGTATTTTTCAACATCTGATCGCCAAAGGCGAAGATA
AAGTCCCGCTGTTAGGCAGTATCCCCGTGATTAAACGCTTATTTAGCCAAAACCGAGATAAAATCTCTAAACGGGAGCTG
GTTATTTTTGTTACGCCTTATATTGTAAAATCTGAAAAAATGGGAGCGGAAAAGCAGAAATAA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (110-175)

• Bacterial type II and III secretion system protein (Secretin) (253-410)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Glaesserella parasuis strain SC1401	96.667	100	0.967
comE	Haemophilus influenzae Rd KW20	52.706	100	0.533
comE	Haemophilus influenzae 86-028NP	51.765	100	0.524
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	37.44	98.571	0.369
pilQ	Vibrio cholerae strain A1552	37.44	98.571	0.369
pilQ	Vibrio campbellii strain DS40M4	36.019	100	0.362