Detailed information NTG0020351

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SMA_1021
• Genome accession: HE613569
• Coordinates: 1005694..1006536 (-)
• Length: 280 a.a.
• NCBI ID: CCF02312.1
• Uniprot ID: -
• Organism: Streptococcus macedonicus ACA-DC 198
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1000694..1011536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMA_1018	-	1001953..1002673 (-)	721	Protein_1017	Hypothetical protein	-
SMA_1019	-	1002673..1003321 (-)	649	Protein_1018	Hypothetical protein	-
SMA_1020	topA	1003458..1005599 (-)	2142	CCF02311.1	DNA topoisomerase I	-
SMA_1021	dprA	1005694..1006536 (-)	843	CCF02312.1	Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake	Machinery gene
SMA_1022	maa	1006610..1007161 (-)	552	CCF02313.1	Maltose O-acetyltransferase	-
SMA_1023	rnhB	1007163..1007942 (-)	780	CCF02314.1	Ribonuclease HII	-
SMA_1024	rbgA	1007929..1008783 (-)	855	CCF02315.1	50S ribosomal subunit maturation GTPase RbgA	-
SMA_1025	-	1009027..1009437 (+)	411	CCF02316.1	Hypothetical protein	-
SMA_1026	-	1009630..1009947 (-)	318	CCF02317.1	Hypothetical protein	-
SMA_1027	-	1010120..1010269 (-)	150	CCF02318.1	Hypothetical protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31005.04 Da
• Isoelectric Point: 8.6600

>NTDB_id=20351 SMA_1021 CCF02312.1 1005694..1006536(-) (dprA) [Streptococcus macedonicus ACA-DC 198]
MNNFELFKLKKAGLTNLNILAILDYQEKQEKSLSLRNMAVVSKCKNPILFMEKYKALDTKELHKEFNRFPSISILDGEYP
LELKYCYNPPVLLFYQGNLELLNRSKMAVVGARTASTTGTKSVQKIIKELGNHFAIVSGLARGIDTSAHLSALKNGGASI
AVIGCGLDVYYPKENKQLQEYMAKNHLVLSEYVAGEAPLKFHFPERNRIIAGLSQGVIVVEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCVISGLDILSEYQI

Nucleotide

• Length: 843 bp

>NTDB_id=20351 SMA_1021 CCF02312.1 1005694..1006536(-) (dprA) [Streptococcus macedonicus ACA-DC 198]
ATGAATAATTTTGAACTGTTTAAATTAAAAAAAGCAGGATTAACAAATCTTAACATTTTAGCTATTTTGGATTATCAAGA
AAAGCAAGAGAAATCACTATCTTTGCGTAATATGGCAGTCGTCTCAAAATGTAAAAATCCTATCCTTTTTATGGAAAAAT
ACAAAGCACTAGACACCAAAGAATTGCACAAAGAATTTAATCGTTTTCCTAGTATTTCCATACTAGATGGCGAATACCCA
TTAGAGCTCAAATATTGTTATAATCCACCTGTTTTGCTGTTTTATCAAGGAAATTTAGAGTTACTCAATCGCTCCAAAAT
GGCGGTGGTAGGAGCGCGAACAGCCTCAACAACAGGAACTAAATCTGTACAGAAAATCATCAAAGAACTCGGAAATCATT
TTGCTATTGTTAGCGGCCTGGCACGTGGCATTGATACCAGTGCGCATTTATCAGCTCTAAAAAACGGTGGTGCATCGATT
GCCGTTATCGGTTGCGGACTGGACGTTTATTATCCCAAAGAAAATAAGCAGTTGCAGGAGTACATGGCTAAAAATCACCT
CGTATTAAGTGAGTACGTAGCAGGAGAAGCACCGCTGAAATTCCATTTTCCAGAGCGAAATCGTATTATTGCAGGTTTAT
CACAAGGCGTTATCGTAGTAGAAGCTAAGCTGCGCTCAGGCAGTTTGATTACGTGCGAAAGAGCATTGGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGAAATATTTTAGATGGAAAATCTGATGGCTGTCATCATTTGATAAAAGAAGGCGCAAAATG
CGTTATATCAGGCTTAGATATCCTTTCGGAATATCAAATATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	73.741	99.286	0.732
dprA/cilB/dalA	Streptococcus mitis SK321	63.441	99.643	0.632
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.214	100	0.632
dprA	Lactococcus lactis subsp. cremoris KW2	61.151	99.286	0.607
dprA	Haemophilus influenzae Rd KW20	38.636	94.286	0.364