Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   DN94_01235 Genome accession   CP007565
Coordinates   214586..215497 (+) Length   303 a.a.
NCBI ID   AHX74410.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain 138spar     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 209586..220497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DN94_01210 - 209813..210304 (+) 492 AHX74405.1 phosphoribosyl carboxyaminoimidazole mutase -
  DN94_01215 - 210291..211364 (+) 1074 AHX74406.1 phosphoribosylaminoimidazole carboxylase -
  DN94_01220 - 211365..212165 (+) 801 AHX74407.1 hypothetical protein -
  DN94_01225 - 212253..212843 (+) 591 AHX74408.1 hypothetical protein -
  DN94_01230 - 213135..214433 (+) 1299 AHX74409.1 adenylosuccinate lyase -
  DN94_01235 comR 214586..215497 (+) 912 AHX74410.1 Cro/Cl family transcriptional regulator Regulator
  - comS 215608..215661 (+) 54 - - Regulator
  DN94_01240 - 215794..216792 (+) 999 AHX74411.1 ATP-dependent DNA helicase RuvB -
  DN94_01245 - 216944..217381 (+) 438 AHX74412.1 phosphotyrosine protein phosphatase -
  DN94_01250 - 217388..217768 (+) 381 AHX74413.1 membrane protein -
  DN94_01255 - 217765..219543 (+) 1779 AHX74414.1 acyltransferase -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35668.18 Da        Isoelectric Point: 5.8492

>NTDB_id=20280 DN94_01235 AHX74410.1 214586..215497(+) (comR) [Streptococcus agalactiae strain 138spar]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YLILRIPTYADAERLKLRECQFDHIFEEFYDNLPEDECLAIDSLQAKFEVYQTGDINFGVEVLCECFDKVKYKEKYTLND
LIIIDLFLTCAVVSKFNNRAFTKEVFQTICKTLISQNHKLTAEDLFWFNHVLLNCVFVGLCLKSEECLAEMLEVSRQTMV
STHDFHKMPLYFMYQWKYFITIDNDIKSAENAYQQSIMFSKMIDDKHLIKKLELEWQEDITGH

Nucleotide


Download         Length: 912 bp        

>NTDB_id=20280 DN94_01235 AHX74410.1 214586..215497(+) (comR) [Streptococcus agalactiae strain 138spar]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TATTTGATTTTAAGAATTCCAACTTATGCAGATGCTGAACGATTAAAATTAAGAGAATGTCAGTTTGATCATATTTTCGA
AGAATTCTATGATAATCTTCCAGAAGACGAATGCTTAGCAATTGACAGTTTACAAGCTAAATTTGAAGTCTATCAAACAG
GAGACATTAATTTTGGTGTGGAGGTTTTATGCGAATGCTTTGATAAAGTAAAATATAAAGAAAAATATACTCTTAATGAT
TTGATTATCATAGATTTGTTTTTAACTTGTGCAGTTGTATCTAAATTTAACAATAGAGCATTTACTAAAGAAGTATTTCA
AACTATATGTAAAACTTTGATAAGTCAGAACCACAAACTTACAGCAGAAGATTTGTTTTGGTTTAATCATGTACTCCTTA
ATTGTGTATTTGTTGGACTTTGTTTAAAGAGTGAAGAGTGTCTTGCAGAAATGTTAGAAGTTAGCCGACAAACGATGGTG
TCAACACATGATTTTCATAAAATGCCTTTATATTTTATGTACCAATGGAAATACTTCATTACAATTGACAATGATATAAA
GTCTGCAGAAAATGCTTACCAACAATCAATTATGTTTTCAAAAATGATTGATGACAAGCATCTAATTAAAAAATTAGAAT
TGGAGTGGCAAGAAGATATAACAGGACATTGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(10-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

53

99.01

0.525
  comR Streptococcus mutans UA159

45.151

98.68

0.446
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

44.674

96.04

0.429
  comR Streptococcus pyogenes MGAS8232

42.574

100

0.426
  comR Streptococcus suis P1/7

37.037

98.02

0.363
  comR Streptococcus suis 05ZYH33

37.037

98.02

0.363

Multiple sequence alignment