Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   Spy49_1248c Genome accession   CP000829
Coordinates   1254628..1255293 (-) Length   221 a.a.
NCBI ID   ACI61533.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1249628..1260293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_1247c - 1254000..1254548 (-) 549 ACI61532.1 Ribosomal subunit interface protein -
  Spy49_1248c comFC/cflB 1254628..1255293 (-) 666 ACI61533.1 Putative late competence protein Machinery gene
  Spy49_1249c comFA/cflA 1255265..1256590 (-) 1326 ACI61534.1 Putative late competence protein required for DNA uptake Machinery gene
  Spy49_1250 - 1256646..1257278 (+) 633 ACI61535.1 Conserved hypothetical protein -
  Spy49_1251 cysM 1257406..1258347 (+) 942 ACI61536.1 Cysteine synthase A -
  Spy49_1252c - 1258365..1258742 (-) 378 ACI61537.1 Putative polyribonucleotide nucleotidyltransferase -
  Spy49_1253c - 1258742..1260142 (-) 1401 ACI61538.1 Hydrolase, haloacid dehalogenase family/peptidyl-prolyl cis-trans isomerase, cyclophilin type -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25189.49 Da        Isoelectric Point: 9.4626

>NTDB_id=20280 Spy49_1248c ACI61533.1 1254628..1255293(-) (comFC/cflB) [Streptococcus pyogenes NZ131]
MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSVCATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNA
AMKAYFSQYKFQGDYLLRKVFAVELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVIYLSLFEKLDNTHQS
SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLSIAR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=20280 Spy49_1248c ACI61533.1 1254628..1255293(-) (comFC/cflB) [Streptococcus pyogenes NZ131]
ATGATCTGTCTACTATGTCAACAAATTAGTCAAACACCAATAAGTATTACAGAAATCATCTTTTTAAGGCGTATCTCTTC
ACCGATTTGTCAACAATGTCAAAAAAGCTTTCAAAAGATAGGAAAAAGTGTTTGTGCGACATGTTGTGCAAACTCAGATA
TAATAGCTTGTCGAGATTGTCTAAAATGGGAAAACAAAGGATACAATGTAAATCATAGAAGCTTATATTGTTATAATGCT
GCTATGAAAGCATACTTCAGTCAATATAAGTTTCAAGGAGACTATTTATTAAGAAAAGTTTTTGCAGTAGAACTTGCCGA
TGTTATTACCAAGTACTATAAAGGCTATATCCCAGTCCCGGTTCCTGTAAGTCCCGGTTGTTTTCGAGAAAGACAATTTA
ATCAAGTGAGCGCTATTCTTGAGGCAGCTAATGTTATCTACCTTTCTCTTTTTGAAAAGCTAGATAATACTCACCAATCT
TCCAGAACAAAAAAAGAGAGATTATTAGTAGAAAAATCTTATCGACTACTAAAAGTATCAAACATTCCTGATAAAATCCT
TATAGTAGATGATATTTATACTACTGGTAGTACAATTATCGCTCTTAGAAAACAATTGGCTAAAGTAGCAAATAGTGACA
TTAAAAGTTTGTCAATTGCACGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae D39

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae R6

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae TIGR4

41.629

100

0.416
  comFC/cflB Streptococcus mitis NCTC 12261

41.176

100

0.412
  comFC/cflB Streptococcus mitis SK321

41.176

100

0.412

Multiple sequence alignment