Detailed information NTG0201680

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: CG712_RS09580
• Genome accession: NZ_CP022547
• Coordinates: 1807448..1809601 (-)
• Length: 717 a.a.
• NCBI ID: WP_024404830.1
• Uniprot ID: A0ABV2EUK0
• Organism: Streptococcus thermophilus strain B59671
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1802448..1814601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CG712_RS10550	-	1802745..1803140 (-)	396	WP_232085807.1	hypothetical protein	-
CG712_RS09555 (CG712_09615)	-	1803339..1803680 (+)	342	WP_024404826.1	LytR/AlgR family response regulator transcription factor	-
CG712_RS09560 (CG712_09620)	comE/blpR	1803682..1804422 (+)	741	WP_096811959.1	response regulator transcription factor	Regulator
CG712_RS09565 (CG712_09625)	-	1804433..1805773 (+)	1341	WP_039671036.1	sensor histidine kinase	-
CG712_RS09570	-	1805821..1805976 (-)	156	WP_096811960.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
CG712_RS09575 (CG712_09630)	comB	1806075..1807436 (-)	1362	WP_096811961.1	bacteriocin secretion accessory protein	Regulator
CG712_RS09580 (CG712_09635)	comA/nlmT	1807448..1809601 (-)	2154	WP_024404830.1	peptide cleavage/export ABC transporter	Regulator
CG712_RS09585 (CG712_09640)	-	1809899..1810156 (+)	258	WP_039671027.1	Blp family class II bacteriocin	-
CG712_RS09590 (CG712_09645)	-	1810173..1810367 (+)	195	WP_039671026.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
CG712_RS09595 (CG712_09650)	-	1810970..1812321 (+)	1352	WP_096811962.1	IS3 family transposase	-
CG712_RS09600 (CG712_09655)	-	1812345..1813172 (+)	828	Protein_1803	type II CRISPR RNA-guided endonuclease Cas9	-
CG712_RS09605 (CG712_09660)	cas1	1813349..1814260 (+)	912	WP_002950323.1	type II CRISPR-associated endonuclease Cas1	-
CG712_RS09610 (CG712_09665)	cas2	1814262..1814585 (+)	324	WP_002946754.1	CRISPR-associated endonuclease Cas2	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80548.46 Da
• Isoelectric Point: 7.1814

>NTDB_id=201680 CG712_RS09580 WP_024404830.1 1807448..1809601(-) (comA/nlmT) [Streptococcus thermophilus strain B59671]
MTAYKRTFVPQIDARDCGVAALASIAKFYGSDYSLAHLRELAKTNKEGTTALGIVKAAKEMGFETRAIQADMSLFDMDDV
PYPFIVHVNKEGKLQHYYVVYHNKKDHLIIGDPDPTVKVTKMTKERFASEWTGVAIFLAPEPSYKPHKDKKNGLMSFLPL
IFRQRALIFYIVLASLLVTLINIGGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILTIVGGVLLVQNTNLFLLSLISVPIYII
IIFAFMKPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKSFKLSKYSILQTTLKQGAQL
ILNIVILWFGAQLVMNGHISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESEFSNSQTLTDSQFL
TGDIRFEDLSYKYGFGRDTLSDINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYKGRITINNNDLKLIDKKTLRQHI
NYLPQQAYIFSGSILENLTLGANQLISQEDIIRACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMAMADKTIIFVAHRLSISERTNQVIVLDQGKVIETGSHHELMTKQGFYHHLFSK

Nucleotide

• Length: 2154 bp

>NTDB_id=201680 CG712_RS09580 WP_024404830.1 1807448..1809601(-) (comA/nlmT) [Streptococcus thermophilus strain B59671]
ATGACAGCTTACAAACGAACTTTTGTTCCTCAAATCGATGCCAGAGACTGTGGTGTGGCTGCTTTAGCCTCTATTGCCAA
GTTTTATGGTTCTGATTATTCCCTAGCTCATTTGAGAGAATTGGCCAAAACCAATAAGGAAGGAACGACCGCTCTTGGTA
TCGTCAAAGCAGCCAAGGAGATGGGCTTTGAAACTAGAGCCATCCAGGCTGACATGAGCCTCTTTGATATGGATGACGTT
CCCTATCCCTTCATCGTTCACGTCAATAAAGAAGGCAAACTGCAACACTACTATGTGGTCTATCACAACAAAAAAGACCA
CCTCATCATTGGTGATCCTGACCCTACGGTCAAAGTCACCAAGATGACCAAGGAGCGGTTTGCTTCTGAATGGACAGGCG
TTGCTATCTTTCTGGCTCCAGAACCCAGCTATAAGCCTCACAAAGATAAAAAGAACGGCCTGATGAGCTTTCTCCCTCTT
ATTTTCAGGCAACGTGCGCTTATCTTTTATATCGTCTTGGCTAGCCTTTTGGTGACACTTATCAATATTGGTGGTTCTTA
CTACCTGCAAGGGATTTTGGATGAATACATTCCTAATCAAATGAAGTCAACCTTGGGGATTATCTCCATCGGCCTGATTA
TCACCTACATCCTCCAGCAGATGATGAGTTTCTCACGAGATTACCTTTTGACTGTGCTCAGCCAGCGGCTAAGCATTGAT
GTGATTCTTTCCTATATCCGTCATATCTTTGAACTGCCCATGTCCTTTTTTGCGACACGGCGGACTGGTGAGGTTATCTC
TCGCTTTACAGATGCCAATTCAATCATTGATGCCCTGGCATCGACCATTTTGTCACTCTTCCTTGATGTCTCTATTTTAA
CCATCGTCGGTGGTGTGCTTTTGGTACAAAACACCAACCTCTTCCTGCTCTCCTTGATTTCAGTTCCCATTTACATCATC
ATTATTTTTGCTTTTATGAAGCCGTTTGAGAAGATGAATAACGATGTGATGCAGAGCAATTCCATGGTCAGCTCTGCCAT
TATCGAAGACATCAACGGCATTGAAACCATCAAATCCTTGACCAGTGAAGAAAGCCGCTACCAGAAGATTGATAGCGAGT
TCGTAGATTACCTGGACAAATCCTTCAAACTCAGTAAATACTCTATCCTGCAAACTACCCTTAAACAGGGAGCTCAGCTC
ATTCTAAATATTGTCATCTTGTGGTTTGGGGCCCAACTAGTCATGAACGGACACATTTCAGTTGGACAACTGATCACCTT
CAACACCCTTCTATCTTATTTTACCAATCCTTTAGAAAATATTATAAACCTCCAAACCAAGCTCCAGTCTGCCAAGGTGG
CTAACAATCGCCTGAATGAAGTCTACCTGGTTGAATCTGAATTCAGTAACAGTCAGACCTTAACAGATTCACAGTTCCTG
ACTGGCGATATTCGCTTTGAAGACCTTTCCTATAAGTACGGTTTCGGACGTGACACCCTATCGGATATCAATCTGACCAT
CAAACAAGGCGATAAGGTCAGTCTAGTGGGAATTAGCGGCTCAGGAAAGACAACCTTGGCCAAGATGATTGTCAATTTCT
TTGAGCCTTACAAGGGTCGAATCACCATCAACAACAATGACCTTAAACTAATTGATAAAAAGACGCTTCGGCAACACATT
AACTACCTCCCACAACAAGCTTATATCTTCAGTGGTTCAATCTTAGAAAACTTGACTTTAGGGGCTAATCAACTGATTAG
TCAGGAAGATATTATCAGAGCTTGTGAGATCGCTGAAATTCGACAAGATATCGAGCAGATGCCTATGGGCTATCAAACAG
AATTGTCTGACGGAGCTGGCTTATCGGGTGGTCAAAAGCAACGGATTGCTTTGGCTAGGGCTCTACTGACTAAAGCCCCT
GTTCTTATTCTTGATGAAGCCACTAGCGGCCTTGATGTGCTAACGGAGAAAAAGGTCATTGATAATTTAATGGCCATGGC
AGACAAGACCATTATCTTTGTCGCACACCGCCTCAGTATTTCTGAGCGAACCAACCAAGTTATCGTTCTTGACCAAGGGA
AGGTCATTGAGACTGGTTCACATCACGAATTGATGACCAAACAAGGTTTCTACCATCATCTATTTAGCAAGTAA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (168-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	73.986	99.721	0.738
comA	Streptococcus mitis NCTC 12261	68.495	99.163	0.679
comA	Streptococcus mitis SK321	67.932	99.163	0.674
comA	Streptococcus pneumoniae Rx1	67.792	99.163	0.672
comA	Streptococcus pneumoniae D39	67.792	99.163	0.672
comA	Streptococcus pneumoniae R6	67.792	99.163	0.672
comA	Streptococcus pneumoniae TIGR4	67.511	99.163	0.669
comA	Streptococcus gordonii str. Challis substr. CH1	65.734	99.721	0.656