Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   CG712_RS09560 Genome accession   NZ_CP022547
Coordinates   1803682..1804422 (+) Length   246 a.a.
NCBI ID   WP_096811959.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain B59671     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1798682..1809422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG712_RS09520 (CG712_09580) - 1798972..1799274 (+) 303 WP_228477331.1 hypothetical protein -
  CG712_RS09525 (CG712_09585) - 1799394..1799573 (+) 180 WP_012775540.1 Blp family class II bacteriocin -
  CG712_RS09535 (CG712_09595) - 1800212..1800574 (+) 363 WP_065973038.1 SAG1252 family conjugative relaxosome accessory protein -
  CG712_RS09540 (CG712_09600) - 1800577..1800942 (+) 366 WP_039671039.1 plasmid mobilization protein -
  CG712_RS09545 (CG712_09605) - 1800929..1802812 (+) 1884 WP_096811958.1 SAG1250 family conjugative relaxase -
  CG712_RS10550 - 1802745..1803140 (-) 396 WP_232085807.1 hypothetical protein -
  CG712_RS09555 (CG712_09615) - 1803339..1803680 (+) 342 WP_024404826.1 LytR/AlgR family response regulator transcription factor -
  CG712_RS09560 (CG712_09620) comE/blpR 1803682..1804422 (+) 741 WP_096811959.1 response regulator transcription factor Regulator
  CG712_RS09565 (CG712_09625) - 1804433..1805773 (+) 1341 WP_039671036.1 sensor histidine kinase -
  CG712_RS09570 - 1805821..1805976 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  CG712_RS09575 (CG712_09630) comB 1806075..1807436 (-) 1362 WP_096811961.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28894.15 Da        Isoelectric Point: 7.2201

>NTDB_id=201678 CG712_RS09560 WP_096811959.1 1803682..1804422(+) (comE/blpR) [Streptococcus thermophilus strain B59671]
MNIFVMEDDFMQQARIEKIITKLLEKHNIVPKKFEISGKPHQLLQAIEEKGVHQLFFLDIEIKEDELKGLQVAKQIREID
PYASIVFVTTHSEFMPLSFRYQVSALDYIDKELGVTEFESRIEAALLHTHNKDNSAVSDDSFYFKSKYAQVQYPFNEVYY
IETSPRPHRVILYTKTDRMEFTASLSDILKQDKRLVQCHRSFAINPRNVVKVDRNEKQIYFPNGATCFISRQKLESTLAV
IDRLHR

Nucleotide


Download         Length: 741 bp        

>NTDB_id=201678 CG712_RS09560 WP_096811959.1 1803682..1804422(+) (comE/blpR) [Streptococcus thermophilus strain B59671]
ATGAATATCTTTGTAATGGAAGATGATTTTATGCAACAAGCGAGAATTGAGAAGATTATTACTAAGCTGTTAGAAAAGCA
CAACATCGTTCCGAAAAAATTTGAAATTTCAGGAAAACCTCATCAGCTACTTCAAGCAATAGAAGAAAAAGGAGTACATC
AGCTCTTCTTTTTAGATATTGAGATTAAGGAAGACGAACTAAAAGGACTTCAAGTCGCTAAACAAATTAGAGAGATTGAC
CCTTATGCTAGTATTGTTTTTGTGACAACACACTCCGAGTTTATGCCCTTATCTTTCAGGTACCAGGTATCTGCCTTGGA
CTATATTGACAAAGAGCTTGGAGTTACCGAATTTGAATCGCGAATAGAAGCAGCTTTACTTCATACTCACAATAAGGACA
ATAGCGCCGTATCGGATGATTCATTCTATTTTAAGTCCAAATATGCTCAAGTACAATACCCATTCAATGAAGTGTACTAC
ATCGAGACTTCTCCCCGCCCTCATCGTGTTATCCTTTATACCAAGACAGACCGAATGGAGTTCACAGCAAGTTTGTCAGA
CATTTTGAAACAAGATAAACGACTTGTACAATGTCATCGTTCGTTTGCAATCAATCCGAGGAATGTTGTTAAAGTGGATA
GAAATGAAAAACAGATCTACTTTCCTAATGGAGCCACCTGTTTTATTTCAAGGCAAAAGCTAGAATCAACTTTAGCTGTT
ATTGATAGACTGCATAGATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.719

98.374

0.528
  comE/comE1 Streptococcus equinus JB1

41.423

97.154

0.402
  comE/comE2 Streptococcus equinus JB1

36.475

99.187

0.362

Multiple sequence alignment