Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   Spy49_1821 Genome accession   CP000829
Coordinates   1813696..1814919 (+) Length   407 a.a.
NCBI ID   ACI62063.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1808696..1819919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_1820c - 1813005..1813484 (-) 480 ACI62062.1 hypothetical protein -
  Spy49_1821 htrA 1813696..1814919 (+) 1224 ACI62063.1 Endopeptidase degP Regulator
  Spy49_1822 spo0J 1814978..1815784 (+) 807 ACI62064.1 Chromosome partitioning protein parB Regulator

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42774.40 Da        Isoelectric Point: 7.3920

>NTDB_id=20168 Spy49_1821 ACI62063.1 1813696..1814919(+) (htrA) [Streptococcus pyogenes NZ131]
MPSMKHILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
TLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=20168 Spy49_1821 ACI62063.1 1813696..1814919(+) (htrA) [Streptococcus pyogenes NZ131]
ATGCCAAGTATGAAACATATCTTAAAATCTTTAAGTATTTTACTAATTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTCAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
ACCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAGTTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGGATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGACTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAACCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGACGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCCACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAACAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(301-396)

Trypsin-like peptidase domain (Trypsin_2)

(109-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.881

99.263

0.614
  htrA Streptococcus gordonii str. Challis substr. CH1

55.224

98.771

0.545
  htrA Streptococcus mitis NCTC 12261

52.826

100

0.528
  htrA Streptococcus pneumoniae Rx1

52.58

100

0.526
  htrA Streptococcus pneumoniae D39

52.58

100

0.526
  htrA Streptococcus pneumoniae R6

52.58

100

0.526
  htrA Streptococcus pneumoniae TIGR4

52.58

100

0.526

Multiple sequence alignment