Detailed information NTG0201658

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB454_RS13720
• Genome accession: NZ_CP017680
• Coordinates: 2642996..2643883 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain CFSAN007851
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2637996..2648883

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB454_RS13685 (AB454_13335)	-	2638014..2638106 (+)	93	WP_010956583.1	hypothetical protein	-
AB454_RS13690 (AB454_13340)	-	2638214..2638711 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB454_RS13695 (AB454_13345)	-	2638721..2638981 (-)	261	WP_001791974.1	hypothetical protein	-
AB454_RS13705 (AB454_13350)	-	2639363..2639476 (-)	114	Protein_2532	hypothetical protein	-
AB454_RS13710 (AB454_13360)	-	2640135..2642135 (-)	2001	WP_000776740.1	ABC transporter permease	-
AB454_RS13715 (AB454_13365)	-	2642132..2642887 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB454_RS13720 (AB454_13370)	braS	2642996..2643883 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB454_RS13725 (AB454_13375)	braR	2643894..2644559 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB454_RS13730 (AB454_13380)	-	2644585..2644785 (-)	201	WP_000604727.1	hypothetical protein	-
AB454_RS13735 (AB454_13390)	-	2644983..2646407 (+)	1425	WP_000953748.1	alkaline phosphatase	-
AB454_RS14370	-	2646477..2646587 (+)	111	WP_001791296.1	hypothetical protein	-
AB454_RS13745 (AB454_13400)	-	2646690..2647145 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB454_RS13750 (AB454_13405)	-	2647390..2648151 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=201658 AB454_RS13720 WP_000143417.1 2642996..2643883(-) (braS) [Staphylococcus aureus strain CFSAN007851]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=201658 AB454_RS13720 WP_000143417.1 2642996..2643883(-) (braS) [Staphylococcus aureus strain CFSAN007851]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99