Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   CG712_RS04420 Genome accession   NZ_CP022547
Coordinates   848007..849374 (-) Length   455 a.a.
NCBI ID   WP_096811636.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain B59671     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 843007..854374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG712_RS04385 (CG712_04420) - 843376..843618 (-) 243 WP_096811635.1 Blp family class II bacteriocin -
  CG712_RS10720 (CG712_04425) - 843869..844270 (-) 402 WP_011226490.1 hypothetical protein -
  CG712_RS04400 (CG712_04435) - 845257..845487 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  CG712_RS04405 (CG712_04440) comE/blpR 845742..846473 (+) 732 WP_002948869.1 LytR/AlgR family response regulator transcription factor Regulator
  CG712_RS10255 comD/blpH 847010..847813 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  CG712_RS04415 (CG712_04450) - 847831..847992 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  CG712_RS04420 (CG712_04455) comB 848007..849374 (-) 1368 WP_096811636.1 bacteriocin secretion accessory protein Regulator
  CG712_RS04425 (CG712_04460) comA/nlmT 849390..851543 (-) 2154 WP_157769910.1 peptide cleavage/export ABC transporter Regulator
  CG712_RS04435 (CG712_04470) - 852557..854302 (-) 1746 WP_096811638.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50369.08 Da        Isoelectric Point: 4.7492

>NTDB_id=201615 CG712_RS04420 WP_096811636.1 848007..849374(-) (comB) [Streptococcus thermophilus strain B59671]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=201615 CG712_RS04420 WP_096811636.1 848007..849374(-) (comB) [Streptococcus thermophilus strain B59671]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGGTTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTACCGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAGGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.468

99.121

0.391
  comB Streptococcus pneumoniae D39

39.468

99.121

0.391
  comB Streptococcus pneumoniae R6

39.468

99.121

0.391
  comB Streptococcus pneumoniae TIGR4

38.803

99.121

0.385
  comB Streptococcus mitis SK321

38.137

99.121

0.378
  comB Streptococcus mitis NCTC 12261

38.137

99.121

0.378